1.2.1.36: retinal dehydrogenase
This is an abbreviated version!
For detailed information about retinal dehydrogenase, go to the full flat file.
Word Map on EC 1.2.1.36
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1.2.1.36
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retinoic
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raldhs
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mesoderm
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dendritic
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all-trans
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aldh1a2
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ventral
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ra-synthesizing
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all-trans-retinoic
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cyp26s
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hindbrain
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retinol-binding
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somite
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anterior-posterior
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gut-homing
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otic
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crabps
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ra-dependent
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ra-responsive
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molecular biology
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somitogenesis
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all-trans-retinal
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rhombomere
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synthesis
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acid-synthesizing
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diagnostics
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dorsoventral
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epicardium
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degradation
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citral
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anteroposterior
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paraxial
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ra-mediated
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rarbeta
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retinyl
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retinoid-dependent
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medicine
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foxp3+
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raralpha
- 1.2.1.36
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retinoic
- raldhs
- mesoderm
- dendritic
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all-trans
- aldh1a2
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ventral
-
ra-synthesizing
-
all-trans-retinoic
-
cyp26s
- hindbrain
-
retinol-binding
- somite
-
anterior-posterior
-
gut-homing
-
otic
-
crabps
-
ra-dependent
-
ra-responsive
- molecular biology
-
somitogenesis
- all-trans-retinal
-
rhombomere
- synthesis
-
acid-synthesizing
- diagnostics
-
dorsoventral
-
epicardium
- degradation
- citral
-
anteroposterior
-
paraxial
-
ra-mediated
-
rarbeta
-
retinyl
-
retinoid-dependent
- medicine
-
foxp3+
-
raralpha
Reaction
Synonyms
aldehyde dehydrogenase 1, aldehyde dehydrogenase 1A1, aldehyde dehydrogenase 1A2, aldehyde dehydrogenase 1A3, ALDH 1A1, ALDH 1A2, ALDH class 1, ALDH-1A1, ALDH-3A1, ALDH1, ALDH1A1, Aldh1a2, Aldh1a3, BcALDH, cytosolic retinal dehydrogenase, dehydrogenase, retinal, dehydrogenase/reductase member 3, DHRS3, ETA-crystallin, More, NAD+-dependent aldehyde dehydrogenase, NAD-dependent retinal dehydrogenase, NAD-dependent retinal dehydrogenases, PB-RALDH, phenobarbital-induced aldehyde dehydrogenase, RALDH, RALDH-1, RALDH-3, RalDH1, RALDH1A1, RALDH2, RALDH3, Raldh4, RDH12, RDH13, RDH5, retialdehyde dehydrogenase, Retinal dehydrogenase, retinal dehydrogenase 1, retinal dehydrogenase 2, retinal dehydrogenase 3, retinal dehydrogenase 4, retinal dehydrogenase 5, retinal dehydrogenase type-2, retinal dehydrogenase-2, retinal dehydrogenase/reductase, retinal short-chain dehydrogenase/reductase, retinalaldehyde dehydrogenase 2, retinaldehyde dehydrogenase, retinaldehyde dehydrogenase 1, retinaldehyde dehydrogenase 2, retinaldehyde dehydrogenase 3, retinaldehyde dehydrogenase type II, retinaldehyde dehydrogenase type-1, retinaldehyde dehydrogenase-2, retinaldehyde dehydrogenases, retinol dehydrogenase 13, retSDR1, testis-specific aldehyde dehydrogenase, thyroid-hormone-binding protein, type 2 retinaldehyde dehydrogenase, xCTBP, xCTBP/xALDH1, zRalDH
ECTree
1.2.1.36 retinal dehydrogenaseAdvanced search results
results (
results (KM Value
KM Value on EC 1.2.1.36 - retinal dehydrogenase
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KM VALUE [mM] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.095
3-deoxyglucosone
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partially purified recombinant ALDH1A1 at pH 7.1 and in the presence of 1 mM NAD
0.0018
12'-apo-beta-carotenal
isoform ALDH1A2, at pH 8.0 and 37°C
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0.003
12'-apo-beta-carotenal
isoform ALDH1A3, at pH 8.0 and 37°C
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0.0034
13-cis retinal
isoform RALDH4, in 100 mM HEPES buffer, pH 8.5, at 37°C
0.005
14'-apo-beta-carotenal
isoform ALDH1A2, at pH 8.0 and 37°C
0.012
14'-apo-beta-carotenal
isoform ALDH1A1, at pH 8.0 and 37°C
0.003
9-cis retinal
isoform RALDH4, in 100 mM HEPES buffer, pH 8.5, at 37°C
0.019
acetaldehyde
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50 mM Tris/HCl buffer, pH 8.0, 3.3 mM pyrazole, 100 mM KCl, 1 mM dithiothreitol, 0.01 mM Zn2+, 12 mM acetaldehyde, 0.015-0.024 mM NAD+
0.024
acetaldehyde
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50 mM Tris/HCl buffer, pH 8.0, 3.3 mM pyrazole, 100 mM KCl, 1 mM dithiothreitol, 0.02 Mn2+, 12 mM acetaldehyde, 0.015-0.024 mM NAD+
0.027
acetaldehyde
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50 mM Tris/HCl buffer, pH 8.0, 3.3 mM pyrazole, 100 mM KCl, 1 mM dithiothreitol, 0.03 mM Ca2+, 12 mM acetaldehyde, 0.015-0.024 mM NAD+
0.028
acetaldehyde
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50 mM Tris/HCl buffer, pH 8.0, 3.3 mM pyrazole, 100 mM KCl, 1 mM dithiothreitol, 0.1 mM Mg2+, 12 mM acetaldehyde, 0.015-0.024 mM NAD+
0.055
acetaldehyde
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50 mM Tris/HCl buffer, pH 8.0, 3.3 mM pyrazole, 100 mM KCl, 1 mM dithiothreitol, 12 mM acetaldehyde, 0.015-0.024 mM NAD+
1.4
acetaldehyde
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50 mM Tris/HCl buffer, pH 8.0, 3.3 mM pyrazole, 100 mM KCl, 1 mM dithiothreitol, 0.3 mM Ca2+, 1-12 mM acetaldehyde, 0.33 mM NAD+
1.8
acetaldehyde
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50 mM Tris/HCl buffer, pH 8.0, 3.3 mM pyrazole, 100 mM KCl, 1 mM dithiothreitol, 0.1 mM Mg2+, 1-12 mM acetaldehyde, 0.33 mM NAD+
2
acetaldehyde
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50 mM Tris/HCl buffer, pH 8.0, 3.3 mM pyrazole, 100 mM KCl, 1 mM dithiothreitol, 0.02 mM Mn2+, 1-12 mM acetaldehyde, 0.33 mM NAD+
2.1
acetaldehyde
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50 mM Tris/HCl buffer, pH 8.0, 3.3 mM pyrazole, 100 mM KCl, 1 mM dithiothreitol, 0.01 mM Zn2+, 1-12 mM acetaldehyde, 0.33 mM NAD+
3.4
acetaldehyde
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50 mM Tris/HCl buffer, pH 8.0, 3.3 mM pyrazole, 100 mM KCl, 1 mM dithiothreitol, 1-12 mM acetaldehyde, 0.33 mM NAD+
0.0039
all-trans retinal
isoform RALDH3, in 10 mM Tris-HCl buffer, pH 8.5, at 37°C
0.0081
all-trans-retinal
pH 8.5, 25°C, recombinant wild-type ALDH1A1 enzyme
0.001
decanal
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recombinant wild-type enzyme and mutant L459F/N460G, pH 8.5, 25°C
0.085
NAD+
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partially purified recombinant ALDH1A1 at pH 7.1 and in the presence of 0.1 mM 3-deoxyglucosone
0.166
NAD+
microsomes, high-fate diet rats, pH and temperature not specified in the publication
0.1822
NAD+
microsomes, control rats, pH and temperature not specified in the publication
0.2269
NAD+
cytosol, control rats, pH and temperature not specified in the publication
0.2424
NAD+
cytosol, high-fate diet rats, pH and temperature not specified in the publication
0.0007
retinal
cellular retinol-binding protein-bound retinal has lower Km of 0.0002 mM
0.001
retinal
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50 mM Tris/HCl buffer, pH 8.0, 3.3 mM pyrazole, 100 mM KCl, 1 mM dithiothreitol, 0.03 mM retinal, 0.056-0.12 mM NAD+
0.0044
retinal
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50 mM Tris/HCl buffer, pH 8.0, 3.3 mM pyrazole, 100 mM KCl, 1 mM dithiothreitol, 0.5 mM Ca2+, 0.03 mM retinal, 0.056-0.12 mM NAD+
0.0046
retinal
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50 mM Tris/HCl buffer, pH 8.0, 3.3 mM pyrazole, 100 mM KCl, 1 mM dithiothreitol, 0.04 mM Mn2+, 0.03 mM retinal, 0.056-0.12 mM NAD+
0.006
retinal
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50 mM Tris/HCl buffer, pH 8.0, 3.3 mM pyrazole, 100 mM KCl, 1 mM dithiothreitol, 0.3 mM Mg2+, 0.03 mM retinal, 0.056-0.12 mM NAD+
0.0064
retinal
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50 mM Tris/HCl buffer, pH 8.0, 3.3 mM pyrazole, 100 mM KCl, 1 mM dithiothreitol, 0.03 mM Zn2+ 0.03 mM retinal, 0.056-0.12 mM NAD+
0.0085
retinal
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retinal bovine serum albumin, Km is 25 times lower than the Km for acetaldehyde
additional information
additional information
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kinetic analysis, isozyme type-2
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additional information
additional information
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kinetics, recombinant wild-type and chimeric mutant enzymes
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additional information
additional information
Michaelis-Menten kinetics
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additional information
additional information
Michaelis-Menten kinetics
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additional information
additional information
Michaelis-Menten kinetics
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additional information
additional information
Michaelis-Menten kinetics and pre-steady-state kinetics
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additional information
additional information
Michaelis-Menten kinetics and pre-steady-state kinetics
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additional information
additional information
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Michaelis-Menten kinetics and pre-steady-state kinetics
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