1.3.99.23: all-trans-retinol 13,14-reductase

This is an abbreviated version!
For detailed information about all-trans-retinol 13,14-reductase, go to the full flat file.

Reaction

Synonyms

(13,14)-all-trans-retinol saturase, 13,14-dihydroretinol saturase, all-trans-13,14-dihydroretinol saturase, all-trans-retinol:all-trans-13,14-dihydroretinol saturase, rat mammary tumor 7, retinol saturase, RetSat, RetSat A, Rmt7

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.99 With unknown physiological acceptors

                1.3.99.23 all-trans-retinol 13,14-reductase

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Results

in table

4

Activating Compound

111

AA Sequence

6

Application

1

CAS Registry Number

8

Cloned(Commentary)

25

Cofactor

31

Disease/ Diagnostics

8

Engineering

10

Expression

20

General Information

1

Inhibitors

9

Localization

3

Molecular Weight [Da]

28

Natural Substrates/ Products (Substrates)

18

Organism

1

Pathway

1

Reaction

9

Reaction Type

17

Reference

47

Source Tissue

42

Substrates and Products (Substrate)

39

Synonyms

1

Systematic Name

Systematic Name

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Systematic Name on EC 1.3.99.23 - all-trans-retinol 13,14-reductase

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SYSTEMATIC NAME

IUBMB Comments

all-trans-13,14-dihydroretinol:acceptor 13,14-oxidoreductase

The reaction is only known to occur in the opposite direction to that given above, with the enzyme being specific for all-trans-retinol as substrate. Neither all-trans-retinoic acid nor 9-cis, 11-cis or 13-cis-retinol isomers are substrates. May play a role in the metabolism of vitamin A.