2.4.1.66: procollagen glucosyltransferase
This is an abbreviated version!
For detailed information about procollagen glucosyltransferase, go to the full flat file.
Word Map on EC 2.4.1.66
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2.4.1.66
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prolyl
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gg
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4-hydroxylase
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galactosyltransferase
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propeptide
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soleus
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aminoterminal
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hyp
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tibialis
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4-hydroxyproline
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chick-embryo
- 2.4.1.66
-
prolyl
- gg
-
4-hydroxylase
-
galactosyltransferase
- propeptide
- soleus
-
aminoterminal
- hyp
- tibialis
- 4-hydroxyproline
-
chick-embryo
Reaction
Synonyms
collagen glucosyltransferase, collagen hydroxylysyl glucosyltransferase, galactosylhydroxylysine glucosyltransferase, galactosylhydroxylysyl glucosyltransferase, GGT, glucosyltransferase, uridine diphosphoglucose-collagen, LH3, LH3/PLOD3, lysyl hydroxylase, lysyl hydroxylase 3, More, multifunctional procollagen lysine hydroxylase and glycosyltransferase, PLOD3, UDP-glucose-collagen glucosyltransferase, UDP-glucose:galactosylhydroxylysine-collagen glucosyltransferase, uridine diphosphoglucose-collagen glucosyltransferase
ECTree
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Localization
Localization on EC 2.4.1.66 - procollagen glucosyltransferase
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5-10% of the total activity is surface-bound, the rest is of cytoplasmic origin
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located within the cisternae of the endoplasmic reticulum
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secretion of the enzyme from the endoplasmic reticulum to the extracellular space occurs via two secretory pathways, which generate two glycoforms. Enzyme molecules found in the cell medium are secreted through the Golgi complex, and the secretion is dependent on lysyl hydroxylase 3 glycosyltransferase activity. Enzyme found on the cell surface bypasses the Golgi complex
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membrane-bound and soluble forms in platelets, lymphocytes and granulocytes
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5-10% of the total activity is surface-bound, the rest is of cytoplasmic origin
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membrane-bound and soluble forms in platelets, lymphocytes and granulocytes
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