1.13.12.16: nitronate monooxygenase

This is an abbreviated version!
For detailed information about nitronate monooxygenase, go to the full flat file.

Word Map on EC 1.13.12.16

Reaction

ethylnitronate
+
O2
=
acetaldehyde
+
nitrite
+
other products

Synonyms

2-nitropropane dioxygenase, NAO, nitroalkane oxidase, nitroalkane-oxidizing enzyme, nitronate monooxygenase, nitropropane dioxygenase, NMO, NMO-Nc, NMO-Ws, nmoA, oxidase, nitroalkane, oxygenase, 2-nitropropane di-, P3N monooxygenase, Pa-NMO, PA4202, protein PA4202, Rv1894c, Sa-NAO

ECTree

     1 Oxidoreductases
         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
             1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
                1.13.12.16 nitronate monooxygenase

Engineering

Engineering on EC 1.13.12.16 - nitronate monooxygenase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
H199A
-
mutant shows no enzymatic function
H196N
H152A
S288A
H179D
mutant enzyme shows no activity. Crystal structure of mutant H179D is determined: The structural superimposition of wild-type Sa-NAO and mutant H179D-nitroethane shows no significant structural variation
H179K
mutant enzyme shows no activity
H179V
mutant enzyme shows no activity
additional information