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1.14.14.47: nitric-oxide synthase (flavodoxin)

This is an abbreviated version!
For detailed information about nitric-oxide synthase (flavodoxin), go to the full flat file.

Word Map on EC 1.14.14.47

Reaction

2 L-arginine + 2 reduced flavodoxin + 2 O2 = 2 Nomega-hydroxy-L-arginine + 2 oxidized flavodoxin + 2 H2O

Synonyms

bNOS, GK1676, nitric oxide synthetase, NO synthase, NOS, SANOS, YumC

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.47 nitric-oxide synthase (flavodoxin)

IC50 Value

IC50 Value on EC 1.14.14.47 - nitric-oxide synthase (flavodoxin)

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0366 - 0.0533
4-methylquinolin-2-amine
0.0027
7-nitroindazole
Bacillus subtilis
chimera between enzyme and flavodoxin YkuN, pH 7.4, 35°C
0.0102
N-omega-nitro-L-arginine
Bacillus subtilis
chimera between enzyme and flavodoxin YkuN, pH 7.4, 35°C
0.0273 - 0.0639
quinolin-2-amine