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1.2.7.3: 2-oxoglutarate synthase

This is an abbreviated version!
For detailed information about 2-oxoglutarate synthase, go to the full flat file.

Word Map on EC 1.2.7.3

Reaction

2-oxoglutarate
+
CoA
+ 2 oxidized ferredoxin =
succinyl-CoA
+
CO2
+ 2 reduced ferredoxin + 2 H+

Synonyms

2-ketoglutarate ferredoxin oxidoreductase, 2-oxoglutarate ferredoxin oxidoreductase, 2-oxoglutarate oxidoreductase, 2-oxoglutarate:ferredoxin 2-oxidoreductase (CoA-succinylating), 2-oxoglutarate:ferredoxin oxidoreductase, alpha-ketoglutarate oxidoreductase, alpha-ketoglutarate synthase, alpha-ketoglutarate-ferredoxin oxidoreductase, CoA-dependent 2-ketoglutarate oxidoreductase, EC 1.2.7.9, FOR enzyme, For(OGOR), forDABGE, KGOR, KOR enzyme, Kor(OGOR), Mmc1_1749, Mmc1_1750, OGOR, OOR, oorDABC

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.7 With an iron-sulfur protein as acceptor
                1.2.7.3 2-oxoglutarate synthase

Expression

Expression on EC 1.2.7.3 - 2-oxoglutarate synthase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
higher specific activity when cultures are grown on peptides-plus-S(0) medium than in cells using maltose as the sole carbon source
-
inducible by growth on aromatic substrates and under denitrifiying conditions 10 to 50fold
O87870; Q8RJQ9
the expression of the oorDABC genes is activated by ferric uptake regulator under iron-replete conditions
the For enzyme is expressed constitutively during oxygen respiration. Little expression of For is observed during cultivation under conditions of nitrate respiration
the Kor enzyme is constitutively expressed during respiration of either oxygen or nitrate respiration