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1.2.7.3: 2-oxoglutarate synthase

This is an abbreviated version!
For detailed information about 2-oxoglutarate synthase, go to the full flat file.

Word Map on EC 1.2.7.3

Reaction

2-oxoglutarate
+
CoA
+ 2 oxidized ferredoxin =
succinyl-CoA
+
CO2
+ 2 reduced ferredoxin + 2 H+

Synonyms

2-ketoglutarate ferredoxin oxidoreductase, 2-oxoglutarate ferredoxin oxidoreductase, 2-oxoglutarate oxidoreductase, 2-oxoglutarate:ferredoxin 2-oxidoreductase (CoA-succinylating), 2-oxoglutarate:ferredoxin oxidoreductase, alpha-ketoglutarate oxidoreductase, alpha-ketoglutarate synthase, alpha-ketoglutarate-ferredoxin oxidoreductase, CoA-dependent 2-ketoglutarate oxidoreductase, EC 1.2.7.9, FOR enzyme, For(OGOR), forDABGE, KGOR, KOR enzyme, Kor(OGOR), Mmc1_1749, Mmc1_1750, OGOR, OOR, oorDABC

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.7 With an iron-sulfur protein as acceptor
                1.2.7.3 2-oxoglutarate synthase

General Stability

General Stability on EC 1.2.7.3 - 2-oxoglutarate synthase

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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
0.5 mM KCl 0.5 M, 10% glycerol 1 mM dithiothreitol, stabilize
O87870; Q8RJQ9
stabilized under anaerobic conditions by a combination of dimercaptoethanol and FeSO4
-
Triton X-100 highly stablizes during purification
-