Reference on EC 2.2.1.1 - transketolase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Teige, M.; Melzer, M.; Suss, K.H.
Purification, properties and in situ localization of the amphibolic enzymes D-ribulose 5-phosphate 3-epimerase and transketolase from spinach chloroplasts
Eur. J. Biochem.
252
237-244
1989
Spinacia oleracea
Racker, E.
Transketolase
The Enzymes, 2nd Ed. (Boyer, P. D. , Lardy, H. , Myrbck, K. , eds. )
5
397-406
1961
Saccharomyces cerevisiae, Cyberlindnera jadinii, Oryctolagus cuniculus, Lactiplantibacillus pentosus, Saccharomyces pastorianus, Spinacia oleracea
-
Domagk, G.F.; Horecker, B.L.
Fructose ane erythrose metabolism in Alcaligensis faecalis
Arch. Biochem. Biophys.
109
342-349
1965
Alcaligenes faecalis
-
Horecker, B.L.; Smyrniotis, P.Z.; Hurwitz, J.
The role of xylulose 5-phosphate in the transketolase reaction
J. Biol. Chem.
223
1009-1019
1956
Rattus norvegicus, Spinacia oleracea
De La Haba, G.; Leder, I.G.; Racker, E.
Crystalline transketolase from bakers yeast: isolation and properties
J. Biol. Chem.
214
409-426
1955
Saccharomyces cerevisiae
Klein, H.; Brand, K.
Purification and properties of transketolase from Candida utilis
Hoppe-Seyler's Z. Physiol. Chem.
358
1325-1337
1977
Cyberlindnera jadinii
Kochetov, G.A.; Philippov, P.P.; Razjivin, A.P.; Tikhomirova, N.K.
Kinetics of reconstruction of holo-transketolase
FEBS Lett.
53
211-212
1975
Saccharomyces cerevisiae
Saitou, S.; Ozawa, T.; Tomita, I.
The purification and some properties of brewers yeast apotransketolase
FEBS Lett.
40
114-118
1974
Saccharomyces pastorianus
Kochetov, G.A.
Determination of transketolase activity via ferricyanide reduction
Methods Enzymol.
89
43-44
1982
Saccharomyces cerevisiae
Egan, R.M.; Sable, H.Z.
Transketolase kinetics. The slow reconstitution of the holoenzyme is due to rate-limiting dimerization of the subunits
J. Biol. Chem.
256
4877-4883
1981
Saccharomyces cerevisiae
Demuynck, C.; Fisson, F.; Bennani-Baiti, I.; Samaki, H.; Mani, J.C.
Immunoaffinity purification of transketolases from yeast and spnich leaves
Agric. Biol. Chem.
54
3073-3078
1990
Saccharomyces cerevisiae, Spinacia oleracea
-
Murphy, D.J.; Walker, D.A.
The properties from transketolase from photosynthetic tissue
Planta
155
316-320
1982
Spinacia oleracea, Triticum aestivum
Kochetov, G.A.
Transketolase from yeast, rat liver, and pig liver
Methods Enzymol.
90
209-223
1982
Saccharomyces cerevisiae, Rattus norvegicus, Sus scrofa
Philippov, P.P.; Shestakova, I.K.; Tikhomirova, N.K.; Kochetov, G.A.
Characterization and properties of pig liver transketolase
Biochim. Biophys. Acta
613
359-369
1980
Sus scrofa
Mocali, A.; Paoletti, F.
Transketolase from human leukocytes. Isolation, properties and induction of polyclonal antibodies
Eur. J. Biochem.
180
213-219
1989
Homo sapiens
Warnock, L.G.; Prudhomme, C.R.
The isolation and preliminary characterization of apotransketolase from human erythrocytes
Biochem. Biophys. Res. Commun.
106
719-723
1982
Homo sapiens
Takeuchi, T.; Nishino, K.; Itokawa, Y.
Purification and characterization of, and preparation of an antibody to, transketolase from human red blood cells
Biochim. Biophys. Acta
872
24-32
1986
Homo sapiens
Paoletti, F.; Aldinucci, D.
Immunoaffinity purification of rat liver transketolase: evidence for multiple forms of the enzyme
Arch. Biochem. Biophys.
245
212-219
1986
Rattus norvegicus
Paoletti, F.
Purification and properties of transketolase from fresh rat liver
Arch. Biochem. Biophys.
222
489-496
1983
Rattus norvegicus
Schellenberg, G.D.; Wilson, N.M.; Copeland, B.R.; Furlong, C.E.
Transketolase from human red blood cells
Methods Enzymol.
90
223-228
1982
Homo sapiens
Kuimov, A.N.; Kovina, M.V.; Kochetov, G.A.
Inhibition of transketolase by N-acetylimidazole
Biochem. Int.
17
517-521
1989
Saccharomyces cerevisiae
Masri, S.W.; Ali, M.; Gubler, C.J.
Isolation of transketolase from rabbit liver and comparison of some of its kinetic properties with transketolase from other sources
Comp. Biochem. Physiol. B
90
167-172
1988
Oryctolagus cuniculus
Blass, J.P.; Piacentini, S.; Boldizsar, E.; Baker, A.
Kinetic studies of mouse brain transketolase
J. Neurochem.
39
729-733
1982
Mus musculus
Heinrich, P.C.; Wiss, O.
Transketolase from human erythrocytes. Purification and properties
Helv. Chim. Acta
54
2658-2668
1971
Homo sapiens
Meshalkina, L.E.; Neef, H.; Tjaglo, M.V.; Schellenberger, A.; Kochetov, G.A.
The presence of a hydroxyl group at the C-1 atom of the transketolase substrate molecule is necessary for the enzyme to perform the transferase reaction
FEBS Lett.
375
220-222
1995
Saccharomyces cerevisiae
Nilsson, U.; Meshalkina, L.; Lindqvist, Y.; Schneider, G.
Examination of substrate binding in thiamin diphosphate-dependent transketolase by protein crystallography and site-directed mutagenesis
J. Biol. Chem.
272
1864-1869
1997
Saccharomyces cerevisiae (P23254), Saccharomyces cerevisiae
Wikner, C.; Nilsson, U.; Meshalkina, L.; Udekwu, C.; Lindqvist, Y.; Schneider, G.
Identification of catalytically important residues in yeast transketolase
Biochemistry
36
15643-15649
1997
Saccharomyces cerevisiae
Soh, Y.; Song, B.J.; Jeng, J.; Kallarakal, A.T.
Critical role of Arg433 in rat transketolase activity as probed by site-directed mutagenesis
Biochem. J.
333
367-372
1998
Rattus norvegicus
-
Nilsson, U.; Hecquet, L.; Gefflaut, T.; Guerard, C.; Schneider, G.
Asp477 is a determinant of the enantioselectivity in yeast transketolase
FEBS Lett.
424
49-52
1998
Saccharomyces cerevisiae
Kovina, M.V.; Tikhonova, O.V.; Solov'eva, O.N.; Bykova, I.A.; Ivanov, A.S.; Kochetov, G.A.
Influence of transketolase substrates on its conformation
Biochem. Biophys. Res. Commun.
275
968-972
2000
Saccharomyces cerevisiae (P23254)
Fiedler, E.; Golbik, R.; Schneider, G.; Tittmann, K.; Neef, H.; Konig, S.; Hubner, G.
Examination of donor substrate conversion in yeast transketolase
J. Biol. Chem.
276
16051-16058
2001
Saccharomyces cerevisiae
Flechner, A.; Dressen, U.; Westhoff, P.; Henze, K.; Schnarrenberger, C.; Martin, W.
Molecular characterization of transketolase (EC 2.2.1.1) active in the Calvin cycle of spinach chloroplasts
Plant Mol. Biol.
32
475-484
1996
Spinacia oleracea
Sprenger, G.A.; Schoerken, U.; Sprenger, G.; Sahm, H.
Transketolase A of Escherichia coli K12. Purification and properties of the enzyme from recombinant strains
Eur. J. Biochem.
230
525-532
1995
Escherichia coli
Gyamerah, M.; Willetts, A.J.
Kinetics of overexpressed transketolase from Escherichia coli JM 107/pQR 700
Enzyme Microb. Technol.
20
127-134
1997
Escherichia coli
-
Schneider, G.; Lindqvist, Y.
Crystallography and mutagenesis of transketolase: mechanistic implications for enzymic thiamin catalysis
Biochim. Biophys. Acta
1385
387-398
1998
Saccharomyces cerevisiae, Escherichia coli
Schenk, G.; Duggleby, R.G.; Nixon, P.F.
Properties and functions of the thiamin diphosphate dependent enzyme transketolase
Int. J. Biochem. Cell Biol.
30
1297-1318
1998
Cyberlindnera jadinii, Oryctolagus cuniculus, Escherichia coli, Homo sapiens, Mus musculus, Rattus norvegicus, Saccharomyces pastorianus, Spinacia oleracea, Sus scrofa, Saccharomyces cerevisiae (P23254), Saccharomyces cerevisiae
Bobst, C.E.; Tabita, F.R.
The role of cysteine 160 in thiamine diphosphate binding of the Calvin-Benson-Bassham cycle transketolase of Rhodobacter sphaeroides
Arch. Biochem. Biophys.
426
43-54
2004
Cereibacter sphaeroides
Veitch, N.J.; Maugeri, D.A.; Cazzulo, J.J.; Lindqvist, Y.; Barrett, M.P.
Transketolase from Leishmania mexicana has a dual subcellular localization
Biochem. J.
382
759-767
2004
Leishmania mexicana (Q8MPM3), Leishmania mexicana
Esakova, O.A.; Meshalkina, L.E.; Golbik, R.; Hubner, G.; Kochetov, G.A.
Donor substrate regulation of transketolase
Eur. J. Biochem.
271
4189-4194
2004
Saccharomyces cerevisiae
Golbik, R.; Meshalkina, L.E.; Sandalova, T.; Tittmann, K.; Fiedler, E.; Neef, H.; Konig, S.; Kluger, R.; Kochetov, G.A.; Schneider, G.; Hubner, G.
Effect of coenzyme modification on the structural and catalytic properties of wild-type transketolase and of the variant E418A from Saccharomyces cerevisiae
Febs J.
272
1326-1342
2005
Saccharomyces cerevisiae
Selivanov, V.A.; Kovina, M.V.; Kochevova, N.V.; Meshalkina, L.E.; Kochetov, G.A.
Kinetic study of the H103A mutant yeast transketolase
FEBS Lett.
567
270-274
2004
Saccharomyces cerevisiae
Selivanov, V.A.; Kovina, M.V.; Kochevova, N.V.; Meshalkina, L.E.; Kochetov, G.A.
Studies of thiamin diphosphate binding to the yeast apotransketolase
J. Mol. Catal. B
26
33-40
2003
Saccharomyces cerevisiae
-
Esakova, O.A.; Khanova, E.A.; Meshalkina, L.E.; Golbik, R.; Huebner, G.; Kochetov, G.A.
Effect of transketolase substrates on holoenzyme reconstitution and stability
Biochemistry
70
770-776
2005
Saccharomyces cerevisiae
Sevostyanova, I.A.; Solovjeva, O.N.; Kochetov, G.A.
Two methods for determination of transketolase activity
Biochemistry
71
560-562
2006
Saccharomyces cerevisiae
Ospanov, R.V.; Kochetov, G.A.; Kurganov, B.I.
Influence of donor substrate on kinetic parameters of thiamine diphosphate binding to transketolase
Biochemistry
72
84-92
2007
Saccharomyces cerevisiae
Smith, M.E.; Kaulmann, U.; Ward, J.M.; Hailes, H.C.
A colorimetric assay for screening transketolase activity
Bioorg. Med. Chem.
14
7062-7065
2006
Escherichia coli
Ospanov, R.; Kochetov, G.; Kurganov, B.
Theoretical model of interactions between ligand-binding sites in a dimeric protein and its application for the analysis of thiamine diphosphate binding to yeast transketolase
Biophys. Chem.
124
106-114
2006
Saccharomyces cerevisiae
Kochetov, G.A.; Sevostyanova, I.A.
Binding of the coenzyme and formation of the transketolase active center
IUBMB Life
57
491-497
2005
Saccharomyces cerevisiae
Boren, J.; Ramos-Montoya, A.; Bosch, K.S.; Vreeling, H.; Jonker, A.; Centelles, J.J.; Cascante, M.; Frederiks, W.M.
In situ localization of transketolase activity in epithelial cells of different rat tissues and subcellularly in liver parenchymal cells
J. Histochem. Cytochem.
54
191-199
2006
Rattus norvegicus
Esakova, O.A.; Meshalkina, L.E.; Kochetov, G.A.
Effects of transketolase cofactors on its conformation and stability
Life Sci.
78
8-13
2005
Saccharomyces cerevisiae
Sevestre, A.; Charmantray, F.; Helaine, V.; Lasikova, A.; Hecquet, L.
Synthesis of stereochemical probes for new fluorogenic assays for yeast transketolase variants
Tetrahedron
62
3969-3976
2006
Saccharomyces cerevisiae
-
Lee, J.Y.; Cheong, D.E.; Kim, G.J.
A novel assay system for the measurement of transketolase activity using xylulokinase from Saccharomyces cerevisiae
Biotechnol. Lett.
30
899-904
2008
Escherichia coli
Voelker, H.U.; Hagemann, C.; Coy, J.; Wittig, R.; Sommer, S.; Stojic, J.; Haubitz, I.; Vince, G.H.; Kaemmerer, U.; Monoranu, C.M.
Expression of transketolase-like 1 and activation of Akt in grade IV glioblastomas compared with grades II and III astrocytic gliomas
Am. J. Clin. Pathol.
130
50-57
2008
Homo sapiens (P51854)
Hu, L.H.; Yang, J.H.; Zhang, D.T.; Zhang, S.; Wang, L.; Cai, P.C.; Zheng, J.F.; Huang, J.S.
The TKTL1 gene influences total transketolase activity and cell proliferation in human colon cancer LoVo cells
Anticancer Drugs
18
427-433
2007
Homo sapiens
Yurshev, V.A.; Sevostyanova, I.A.; Solovjeva, O.N.; Zabrodskaya, S.V.; Kochetov, G.A.
Nonequivalence of transketolase active centers with respect to acceptor substrate binding
Biochem. Biophys. Res. Commun.
361
1044-1047
2007
Saccharomyces cerevisiae
Meshalkina, L.E.; Kochetov, G.A.; Brauer, J.; Huebner, G.; Tittmann, K.; Golbik, R.
New evidence for cofactors amino group function in thiamin catalysis by transketolase
Biochem. Biophys. Res. Commun.
366
692-697
2008
Saccharomyces cerevisiae
Asztalos, P.; Parthier, C.; Golbik, R.; Kleinschmidt, M.; Huebner, G.; Weiss, M.S.; Friedemann, R.; Wille, G.; Tittmann, K.
Strain and near attack conformers in enzymic thiamin catalysis: X-ray crystallographic snapshots of bacterial transketolase in covalent complex with donor ketoses xylulose 5-phosphate and fructose 6-phosphate, and in noncovalent complex with acceptor aldose ribose 5-phosphate
Biochemistry
46
12037-12052
2007
Escherichia coli (P27302), Escherichia coli
Ospanov, R.V.; Kochetov, G.A.; Kurganov, B.I.
Influence of donor substrate on kinetic parameters of thiamine diphosphate binding to transketolase
Biochemistry (Moscow)
72
84-92
2007
Saccharomyces cerevisiae
Thomas, A.A.; Le Huerou, Y.; De Meese, J.; Gunawardana, I.; Kaplan, T.; Romoff, T.T.; Gonzales, S.S.; Condroski, K.; Boyd, S.A.; Ballard, J.; Bernat, B.; DeWolf, W.; Han, M.; Lee, P.; Lemieux, C.; Pedersen, R.; Pheneger, J.; Poch, G.; Smith, D.; Sullivan, F.; Weiler, S.; Wright, S.K.; Lin, J.; Brandhuber, B.; Vigers, G.
Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors
Bioorg. Med. Chem. Lett.
18
2206-2210
2008
Homo sapiens
Le Huerou, Y.; Gunawardana, I.; Thomas, A.A.; Boyd, S.A.; de Meese, J.; Dewolf, W.; Gonzales, S.S.; Han, M.; Hayter, L.; Kaplan, T.; Lemieux, C.; Lee, P.; Pheneger, J.; Poch, G.; Romoff, T.T.; Sullivan, F.; Weiler, S.; Wright, S.K.; Lin, J.
Prodrug thiamine analogs as inhibitors of the enzyme transketolase
Bioorg. Med. Chem. Lett.
18
505-508
2008
Mus musculus (P40142), Mus musculus Balb-c (P40142)
Thomas, A.A.; De Meese, J.; Le Huerou, Y.; Boyd, S.A.; Romoff, T.T.; Gonzales, S.S.; Gunawardana, I.; Kaplan, T.; Sullivan, F.; Condroski, K.; Lyssikatos, J.P.; Aicher, T.D.; Ballard, J.; Bernat, B.; DeWolf, W.; Han, M.; Lemieux, C.; Smith, D.; Weiler, S.; Wright, S.K.; Vigers, G.; Brandhuber, B.
Non-charged thiamine analogs as inhibitors of enzyme transketolase
Bioorg. Med. Chem. Lett.
18
509-512
2008
Homo sapiens
Aucamp, J.P.; Martinez-Torres, R.J.; Hibbert, E.G.; Dalby, P.A.
A microplate-based evaluation of complex denaturation pathways: structural stability of Escherichia coli transketolase
Biotechnol. Bioeng.
99
1303-1310
2008
Escherichia coli
Miller, O.J.; Hibbert, E.G.; Ingram, C.U.; Lye, G.J.; Dalby, P.A.
Optimisation and evaluation of a generic microplate-based HPLC screen for transketolase activity
Biotechnol. Lett.
29
1759-1770
2007
Escherichia coli
Zerilli, M.; Amato, M.C.; Martorana, A.; Cabibi, D.; Coy, J.F.; Cappello, F.; Pompei, G.; Russo, A.; Giordano, C.; Rodolico, V.
Increased expression of transketolase-like-1 in papillary thyroid carcinomas smaller than 1.5 cm in diameter is associated with lymph-node metastases
Cancer
113
936-944
2008
Homo sapiens
Zhang, S.; Yue, J.X.; Yang, J.H.; Cai, P.C.; Kong, W.J.
Overexpression of transketolase protein TKTL1 is associated with occurrence and progression in nasopharyngeal carcinoma: a potential therapeutic target in nasopharyngeal carcinoma
Cancer Biol. Ther.
7
517-522
2008
Homo sapiens (P51854), Homo sapiens (Q9H0I9), Homo sapiens
Chen, B.H.; Baganz, F.; Woodley, J.M.
Modelling and optimization of a transketolase-mediated carbon-carbon bond formation reaction
Chem. Eng. Sci.
62
3178-3184
2007
synthetic construct
-
Martinez-Torres, R.J.; Aucamp, J.P.; George, R.; Dalby, P.A.
Structural stability of E. coli transketolase to urea denaturation
Enzyme Microb. Technol.
41
653-662
2007
Escherichia coli (P27302)
-
Voelker, H.U.; Scheich, M.; Schmausser, B.; Kaemmerer, U.; Eck, M.
Overexpression of transketolase TKTL1 is associated with shorter survival in laryngeal squamous cell carcinomas
Eur. Arch. Otorhinolaryngol.
264
1431-1436
2007
Homo sapiens
Lonsdale, D.
Three case reports to illustrate clinical applications in the use of erythrocyte transketolase
Evid. Based. Complement Alternat. Med.
4
247-250
2006
Homo sapiens
Alexander-Kaufman, K.; Harper, C.
Transketolase: Observations in alcohol-related brain damage research
Int. J. Biochem. Cell Biol.
41
717-720
2009
Escherichia coli, Homo sapiens
Krockenberger, M.; Honig, A.; Rieger, L.; Coy, J.F.; Sutterlin, M.; Kapp, M.; Horn, E.; Dietl, J.; Kammerer, U.
Transketolase-like 1 expression correlates with subtypes of ovarian cancer and the presence of distant metastases
Int. J. Gynecol. Cancer
17
101-106
2007
Homo sapiens
Froehlich, E.; Fink, I.; Wahl, R.
Is transketolase like 1 a target for the treatment of differentiated thyroid carcinoma? A study on thyroid cancer cell lines
Invest. New Drugs
27
297-303
2009
Homo sapiens
Naula, C.; Alibu, V.P.; Brock, J.M.; Veitch, N.J.; Burchmore, R.J.; Barrett, M.P.
A new erythrose 4-phosphate dehydrogenase coupled assay for transketolase
J. Biochem. Biophys. Methods
70
1185-1187
2008
Leishmania mexicana (Q8MPM3), Leishmania mexicana
Hibbert, E.G.; Senussi, T.; Costelloe, S.J.; Lei, W.; Smith, M.E.; Ward, J.M.; Hailes, H.C.; Dalby, P.A.
Directed evolution of transketolase activity on non-phosphorylated substrates
J. Biotechnol.
131
425-432
2007
Escherichia coli
Hibbert, E.G.; Senussi, T.; Smith, M.E.; Costelloe, S.J.; Ward, J.M.; Hailes, H.C.; Dalby, P.A.
Directed evolution of transketolase substrate specificity towards an aliphatic aldehyde
J. Biotechnol.
134
240-245
2008
Escherichia coli
Kohrenhagen, N.; Voelker, H.U.; Schmidt, M.; Kapp, M.; Krockenberger, M.; Frambach, T.; Dietl, J.; Kammerer, U.
Expression of transketolase-like 1 (TKTL1) and p-Akt correlates with the progression of cervical neoplasia
J. Obstet. Gynaecol. Res.
34
293-300
2008
Homo sapiens (P51854)
Joshi, S.; Singh, A.R.; Kumar, A.; Misra, P.C.; Siddiqi, M.I.; Saxena, J.K.
Molecular cloning and characterization of Plasmodium falciparum transketolase
Mol. Biochem. Parasitol.
160
32-41
2008
Plasmodium falciparum
Lovato, L.; Cianti, R.; Gini, B.; Marconi, S.; Bianchi, L.; Armini, A.; Anghileri, E.; Locatelli, F.; Paoletti, F.; Franciotta, D.; Bini, L.; Bonetti, B.
Transketolase and CNPase I are specifically recognized by IgG autoantibodies in multiple sclerosis patients
Mol. Cell. Proteomics
7
2337-2349
2008
Homo sapiens (P29401), Homo sapiens
Domain, F.; Bina, X.R.; Levy, S.B.
Transketolase A, an enzyme in central metabolism, derepresses the marRAB multiple antibiotic resistance operon of Escherichia coli by interaction with MarR
Mol. Microbiol.
66
383-394
2007
Escherichia coli
Harinarayanan, R.; Murphy, H.; Cashel, M.
Synthetic growth phenotypes of Escherichia coli lacking ppGpp and transketolase A (tktA) are due to ppGpp-mediated transcriptional regulation of tktB
Mol. Microbiol.
69
882-894
2008
Escherichia coli (P27302), Escherichia coli (P33570), Escherichia coli
Foeldi, M.; Stickeler, E.; Bau, L.; Kretz, O.; Watermann, D.; Gitsch, G.; Kayser, G.; Zur Hausen, A.; Coy, J.F.
Transketolase protein TKTL1 overexpression: A potential biomarker and therapeutic target in breast cancer
Oncol. Rep.
17
841-845
2007
Homo sapiens
Sevostyanova, I.A.; Yurshev, V.A.; Solovjeva, O.N.; Zabrodskaya, S.V.; Kochetov, G.A.
Effect of bivalent cations on the interaction of transketolase with its donor substrate
Proteins
71
541-545
2008
Saccharomyces cerevisiae
Oh, S.H.; Witek, R.P.; Bae, S.H.; Darwiche, H.A.; Jung, Y.; Pi, L.; Brown, A.; Petersen, B.E.
Detection of transketolase in bone marrow-derived insulin producing cells: Benfotiamine enhances insulin synthesis and glucose metabolism
Stem Cells Dev.
18
37-46
2009
Rattus norvegicus
Charmantray, F.; Helaine, V.; Lasikova, A.; Legeret, B.; Hecquet, L.
Chemoenzymatic synthesis of L-tyrosine derivative for a transketolase assay
Tetrahedron Lett.
49
3229-3233
2008
Saccharomyces cerevisiae
-
Smith, M.; Hibbert, E.; Jones, A.; Dalby, P.; Hailesa, H.
Enhancing and reversing the stereoselectivity of Escherichia coli transketolase via single-point mutations
Adv. Synth. Catal.
350
2631-2638
2008
Escherichia coli
-
Sayar, N.; Chen, B.; Lye, G.; Woodley, J.
Modelling and simulation of a transketolase mediated reaction: Sensitivity analysis of kinetic parameters
Biochem. Eng. J.
47
1-9
2009
Escherichia coli
-
Sayar, N.; Chen, B.; Lye, G.; Woodley, J.
Process modelling and simulation of a transketolase mediated reaction: Analysis of alternative modes of operation
Biochem. Eng. J.
47
10-18
2009
Escherichia coli
-
Sevostyanova, I.A.; Selivanov, V.A.; Yurshev, V.A.; Solovjeva, O.N.; Zabrodskaya, S.V.; Kochetov, G.A.
Cooperative binding of substrates to transketolase from Saccharomyces cerevisiae
Biochemistry (Moscow)
74
789-792
2009
Saccharomyces cerevisiae
Matosevic, S.; Lye, G.J.; Baganz, F.
Design and characterization of a prototype enzyme microreactor: Quantification of immobilized transketolase kinetics
Biotechnol. Prog.
26
118-126
2009
Escherichia coli
Wu, H.T.; Allie, N.; Myer, L.; Govender, D.
Anaplastic nephroblastomas express transketolase-like enzyme 1
J. Clin. Pathol.
62
460-463
2009
Homo sapiens
Chen, H.; Yue, J.; Yang, S.; Ding, H.; Zhao, R.; Zhang, S.
Overexpression of transketolase-like gene 1 is associated with cell proliferation in uterine cervix cancer
J. Exp. Clin. Cancer Res.
28
43-55
2009
Homo sapiens (P51854), Homo sapiens
Obiol-Pardo, C.; Rubio-Martinez, J.
Homology modeling of human transketolase: description of critical sites useful for drug design and study of the cofactor binding mode
J. Mol. Graph. Model.
27
723-734
2009
Homo sapiens
Zhao, Y.; Pan, X.; Zhao, J.; Wang, Y.; Peng, Y.; Zhong, C.
Decreased transketolase activity contributes to impaired hippocampal neurogenesis induced by thiamine deficiency
J. Neurochem.
111
537-546
2009
Mus musculus
Willige, B.C.; Kutzer, M.; Tebartz, F.; Bartels, D.
Subcellular localization and enzymatic properties of differentially expressed transketolase genes isolated from the desiccation tolerant resurrection plant Craterostigma plantagineum
Planta
229
659-666
2009
Craterostigma plantagineum
Sawada, K.; Taki, A.; Yamakawa, T.; Seki, M.
Key role for transketolase activity in erythritol production by Trichosporonoides megachiliensis SN-G42
J. Biosci. Bioeng.
108
385-390
2009
Moniliella megachiliensis, Moniliella megachiliensis SN-G42
Horsham, M.; Saxby, H.; Blake, J.; Isaacs, N.W.; Mitchell, T.J.; Riboldi-Tunnicliffe, A.
Expression, purification, crystallization and preliminary X-ray crystallographic data from TktA, a transketolase from the lactic acid bacterium Lactobacillus salivarius
Acta Crystallogr. Sect. F
66
899-901
2010
Ligilactobacillus salivarius (Q1WQU8), Ligilactobacillus salivarius
Meshalkina, L.E.; Solovjeva, O.N.; Kochetov, G.A.
Interaction of transketolase from human tissues with substrates
Biochemistry (Moscow)
76
1061-1064
2011
Homo sapiens
Meshalkina, L.E.; Solovjeva, O.N.; Khodak, Y.A.; Drutsa, V.L.; Kochetov, G.A.
Isolation and properties of human transketolase
Biochemistry (Moscow)
75
873-880
2010
Homo sapiens
Kim, Y.; Kim, E.Y.; Seo, Y.M.; Yoon, T.K.; Lee, W.S.; Lee, K.A.
Function of the pentose phosphate pathway and its key enzyme, transketolase, in the regulation of the meiotic cell cycle in oocytes
Clin. Exp. Reprod. Med.
39
58-67
2012
Mus musculus
Matsushika, A.; Goshima, T.; Fujii, T.; Inoue, H.; Sawayama, S.; Yano, S.
Characterization of non-oxidative transaldolase and transketolase enzymes in the pentose phosphate pathway with regard to xylose utilization by recombinant Saccharomyces cerevisiae
Enzyme Microb. Technol.
51
16-25
2012
Saccharomyces cerevisiae (P23254), Saccharomyces cerevisiae (P33315), Saccharomyces cerevisiae
Mitschke, L.; Parthier, C.; Schroeder-Tittmann, K.; Coy, J.; Luedtke, S.; Tittmann, K.
The crystal structure of human transketolase and new insights into its mode of action
J. Biol. Chem.
285
31559-31570
2010
Homo sapiens (P29401), Homo sapiens
Jahromi, R.R.; Morris, P.; Martinez-Torres, R.J.; Dalby, P.A.
Structural stability of E. coli transketolase to temperature and pH denaturation
J. Biotechnol.
155
209-216
2011
Escherichia coli
Stoffel, S.A.; Alibu, V.P.; Hubert, J.; Ebikeme, C.; Portais, J.C.; Bringaud, F.; Schweingruber, M.E.; Barrett, M.P.
Transketolase in Trypanosoma brucei
Mol. Biochem. Parasitol.
179
1-7
2011
Trypanosoma brucei
Domain, F.; Bina, X.; Levy, S.
Transketolase A, an enzyme in central metabolism, derepresses the marRAB multiple antibiotic resistance operon of Escherichia coli by interaction with MarR
Mol. Microbiol.
80
853-853
2011
Escherichia coli
Fullam, E.; Pojer, F.; Bergfors, T.; Jones, T.; Cole, S.
Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme
Open Biology
2
110026
2012
Mycobacterium tuberculosis (P9WG25), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WG25)
Hu, C.W.; Chang, Y.L.; Chen, S.J.; Kuo-Huang, L.L.; Liao, J.C.; Huang, H.C.; Juan, H.F.
Revealing the functions of the transketolase enzyme isoforms in Rhodopseudomonas palustris using a systems biology approach
PLoS ONE
6
e28329
2011
Rhodopseudomonas palustris
Obiol-Pardo, C.; Alcarraz-Vizan, G.; Cascante, M.; Rubio-Martinez, J.
Diphenyl urea derivatives as inhibitors of transketolase: a structure-based virtual screening
PLoS ONE
7
e32276
2012
Homo sapiens (P29401), Homo sapiens
Solovjeva, O.N.; Sevostyanova, I.A.; Yurshev, V.A.; Selivanov, V.A.; Kochetov, G.A.
Effects of free Ca2+ on kinetic characteristics of holotransketolase
Protein J.
31
137-140
2012
Saccharomyces cerevisiae
Ranoux, A.; Arends, I.; Hanefeld, U.
Development of screening methods for transketolase activity and substrate scope
Tetrahedron Lett.
53
790-793
2012
Saccharomyces cerevisiae, Escherichia coli
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Lukacik, P.; Lobley, C.M.; Bumann, M.; Arena de Souza, V.; Owens, R.J.; OToole, P.W.; Walsh, M.A.
High-resolution structures of Lactobacillus salivarius transketolase in the presence and absence of thiamine pyrophosphate
Acta Crystallogr. Sect. F
71
1327-1334
2015
Ligilactobacillus salivarius (Q1WQU8), Ligilactobacillus salivarius, Ligilactobacillus salivarius UCC118 (Q1WQU8), Ligilactobacillus salivarius UCC118
Abdoul-Zabar, J.; Sorel, I.; Helaine, V.; Charmantray, F.; Devamani, T.; Yi, D.; De Berardinis, V.; Louis, D.; Marliere, P.; Fessner, W.; Hecquet, L.
Thermostable transketolase from Geobacillus stearothermophilus: Characterization and catalytic properties
Adv. Synth. Catal.
355
116-128
2013
Geobacillus stearothermophilus (A0A0I9QGZ2)
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Abdoul Zabar, J.; Lorilliere, M.; Yi, D.; Thangavelu, S.; Devamani, T.; Nauton, L.; Charmantray, F.; Helaine, V.; Fessner, W.; Hecquet, L.
Engineering a thermostable transketolase for unnatural conversion of (2S)-hydroxyaldehydes
Adv. Synth. Catal.
357
1715-1720
2015
Geobacillus stearothermophilus (A0A0I9QGZ2)
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Kochetov, G.A.; Solovjeva, O.N.
Structure and functioning mechanism of transketolase
Biochim. Biophys. Acta
1844
1608-1618
2014
Saccharomyces cerevisiae (P23254), Saccharomyces cerevisiae
Solovjeva, O.N.; Kovina, M.V.; Kochetov, G.A.
Substrate inhibition of transketolase
Biochim. Biophys. Acta
1864
280-282
2016
Saccharomyces cerevisiae (P23254)
Markert, B.; Stolzenberger, J.; Brautaset, T.; Wendisch, V.F.
Characterization of two transketolases encoded on the chromosome and the plasmid pBM19 of the facultative ribulose monophosphate cycle methylotroph Bacillus methanolicus
BMC Microbiol.
14
7
2014
Bacillus methanolicus, Bacillus methanolicus MGA3
Yi, D.; Saravanan, T.; Devamani, T.; Charmantray, F.; Hecquet, L.; Fessner, W.D.
A thermostable transketolase evolved for aliphatic aldehyde acceptors
Chem. Commun. (Camb.)
51
480-483
2015
Geobacillus stearothermophilus (A0A0I9QGZ2), Geobacillus stearothermophilus
Ali, G.; Moreau, T.; Forano, C.; Mousty, C.; Prevot, V.; Charmantray, F.; Hecquet, L.
Chiral polyol synthesis catalyzed by a thermostable transketolase immobilized on layered double hydroxides in ionic liquids
ChemCatChem
7
3163-3170
2015
Geobacillus stearothermophilus (A0A0I9QGZ2)
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Sheng, X.; Liu, Y.; Liu, C.
Theoretical studies on the common catalytic mechanism of transketolase by using simplified models
J. Mol. Graph. Model.
39
23-28
2013
Homo sapiens (P29401)
Vimala, A.; Harinarayanan, R.
Transketolase activity modulates glycerol-3-phosphate levels in Escherichia coli
Mol. Microbiol.
100
263-277
2016
Escherichia coli, Escherichia coli AV139
Khozaei, M.; Fisk, S.; Lawson, T.; Gibon, Y.; Sulpice, R.; Stitt, M.; Lefebvre, S.C.; Raines, C.A.
Overexpression of plastid transketolase in tobacco results in a thiamine auxotrophic phenotype
Plant Cell
27
432-447
2015
Arabidopsis thaliana
Bi, H.; Wang, M.; Dong, X.; Ai, X.
Cloning and expression analysis of transketolase gene in Cucumis sativus L.
Plant Physiol. Biochem.
70
512-521
2013
Cucumis sativus (G8EX76), Cucumis sativus
Xu, I.M.; Lai, R.K.; Lin, S.H.; Tse, A.P.; Chiu, D.K.; Koh, H.Y.; Law, C.T.; Wong, C.M.; Cai, Z.; Wong, C.C.; Ng, I.O.
Transketolase counteracts oxidative stress to drive cancer development
Proc. Natl. Acad. Sci. USA
113
725-734
2016
Homo sapiens
Kalhori, N.; Nulit, R.; Go, R.
Cloning, expression and characterization of sugarcane (Saccharum officinarum L.) transketolase
Protein J.
32
551-559
2013
Saccharum officinarum
Iwata, H.; Kobayashi, Y.; Mizushima, D.; Watanabe, T.; Ogihara, J.; Kasumi, T.
Complementary function of two transketolase isoforms from Moniliella megachiliensis in relation to stress response
AMB Express
7
45
2017
Moniliella megachiliensis (A0A1L7NSX5), Moniliella megachiliensis (A0A1L7NSY2), Moniliella megachiliensis, Moniliella megachiliensis SN-124A (A0A1L7NSX5), Moniliella megachiliensis SN-124A (A0A1L7NSY2)
Pasquini, M.; Fermani, S.; Tedesco, D.; Sciabolini, C.; Crozet, P.; Naldi, M.; Henri, J.; Vothknecht, U.; Bertucci, C.; Lemaire, S.D.; Zaffagnini, M.; Francia, F.
Structural basis for the magnesium-dependent activation of transketolase from Chlamydomonas reinhardtii
Biochim. Biophys. Acta
1861
2132-2145
2017
Chlamydomonas reinhardtii (A8IAN1), Chlamydomonas reinhardtii
Solovjeva, O.N.; Kovina, M.V.; Zavialova, M.G.; Zgoda, V.G.; Shcherbinin, D.S.; Kochetov, G.A.
New in the mechanism of one-substrate transketolase reaction
Biosci. Rep.
40
BSR20180246
2018
Saccharomyces cerevisiae
Henriquez, M.J.; Braun-Galleani, S.; Nesbeth, D.N.
Whole cell biosynthetic activity of Komagataella phaffii (Pichia pastoris) GS115 strains engineered with transgenes encoding Chromobacterium violaceum omega-transaminase alone or combined with native transketolase
Biotechnol. Prog.
36
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2020
Chromobacterium violaceum
Shi, J.; Wang, W.; Lin, Y.; Xu, K.; Xu, Y.; Ji, D.; Chen, C.; Xie, C.
Insight into transketolase of Pyropia haitanensis under desiccation stress based on integrative analysis of omics and transformation
BMC Plant Biol.
19
475
2019
Neoporphyra haitanensis
Zhou, C.; Saravanan, T.; Lorilliere, M.; Wei, D.; Charmantray, F.; Hecquet, L.; Fessner, W.D.; Yi, D.
Second-generation engineering of a thermostable transketolase (TKGst) for aliphatic aldehyde acceptors with either improved or reversed stereoselectivity
ChemBioChem
18
455-459
2017
Geobacillus stearothermophilus
Baierl, A.; Theorell, A.; Mackfeld, U.; Marquardt, P.; Hoffmann, F.; Moers, S.; Noeh, K.; Buchholz, P.; Pleiss, J.; Pohl, M.
Towards a mechanistic understanding of factors controlling the stereoselectivity of transketolase
ChemCatChem
10
2601-2611
2018
Escherichia coli (P27302)
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Prejano, M.; Medina, F.E.; Fernandes, P.A.; Russo, N.; Ramos, M.J.; Marino, T.
The catalytic mechanism of human transketolase
Chemphyschem
20
2881-2886
2019
Homo sapiens (P29401), Homo sapiens
Ricciardelli, C.; Lokman, N.A.; Cheruvu, S.; Tan, I.A.; Ween, M.P.; Pyragius, C.E.; Ruszkiewicz, A.; Hoffmann, P.; Oehler, M.K.
Transketolase is upregulated in metastatic peritoneal implants and promotes ovarian cancer cell proliferation
Clin. Exp. Metastasis
32
441-455
2015
Homo sapiens
Payongsri, P.; Steadman, D.; Hailes, H.C.; Dalby, P.A.
Second generation engineering of transketolase for polar aromatic aldehyde substrates
Enzyme Microb. Technol.
71
45-52
2015
Escherichia coli
Yu, H.; Hernandez Lopez, R.I.; Steadman, D.; Mendez-Sanchez, D.; Higson, S.; Cazares-Koerner, A.; Sheppard, T.D.; Ward, J.M.; Hailes, H.C.; Dalby, P.A.
Engineering transketolase to accept both unnatural donor and acceptor substrates and produce alpha-hydroxyketones
FEBS J.
287
1758-1776
2020
Escherichia coli (P27302)
Subrizi, F.; Cardenas-Fernandez, M.; Lye, G.; Ward, J.; Dalby, P.; Sheppard, T.; Hailes, H.
Transketolase catalysed upgrading of L-arabinose The one-step stereoselective synthesis of L-gluco-heptulose
Green Chem.
18
3158-3165
2016
Escherichia coli (P27302)
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Saravanan, T.; Reif, M.; Yi, D.; Lorilliere, M.; Charmantray, F.; Hecquet, L.; Fessner, W.
Engineering a thermostable transketolase for arylated substrates
Green Chem.
19
481-489
2017
Geobacillus stearothermophilus
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Klaus, A.; Pfirrmann, T.; Glomb, M.A.
Transketolase A from E. coli significantly suppresses protein glycation by glycolaldehyde and glyoxal in vitro
J. Agric. Food Chem.
65
8196-8202
2017
Escherichia coli (P27302), Escherichia coli
Shaw, J.A.; Henard, C.A.; Liu, L.; Dieckman, L.M.; Vazquez-Torres, A.; Bourret, T.J.
Salmonella enterica serovar Typhimurium has three transketolase enzymes contributing to the pentose phosphate pathway
J. Biol. Chem.
293
11271-11282
2018
Salmonella enterica subsp. enterica serovar Typhimurium (A0A0F6B484 and A0A0F6B483), Salmonella enterica subsp. enterica serovar Typhimurium (A0A0F6B4M5), Salmonella enterica subsp. enterica serovar Typhimurium (A0A0F6B6H7), Salmonella enterica subsp. enterica serovar Typhimurium, Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028s (A0A0F6B484 and A0A0F6B483), Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028s (A0A0F6B4M5), Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028s (A0A0F6B6H7)
Zhang, Q.; Linnemann, T.V.; Schreiber, L.; Bartels, D.
The role of transketolase and octulose in the resurrection plant Craterostigma plantagineum
J. Exp. Bot.
67
3551-3559
2016
Craterostigma plantagineum
Huo, J.; Zhao, B.; Zhang, Z.; Xing, J.; Zhang, J.; Dong, J.; Fan, Z.
Structure-based discovery and synthesis of potential transketolase inhibitors
Molecules
23
2116
2018
Arabidopsis thaliana
Mesquita, A.; Tabara, L.C.; Martinez-Costa, O.; Santos-Rodrigo, N.; Vincent, O.; Escalante, R.
Dissecting the function of Atg1 complex in Dictyostelium autophagy reveals a connection with the pentose phosphate pathway enzyme transketolase
Open Biology
5
150088
2015
Homo sapiens
Bi, H.; Li, F.; Wang, H.; Ai, X.
Overexpression of transketolase gene promotes chilling tolerance by increasing the activities of photosynthetic enzymes, alleviating oxidative damage and stabilizing cell structure in Cucumis sativus L.
Physiol. Plant.
167
502-515
2019
Cucumis sativus
Hsu, L.J.; Hsu, N.S.; Wang, Y.L.; Wu, C.J.; Li, T.L.
Structural and biochemical interrogation on transketolase from Pichia stipitis for new functionality
Protein Eng. Des. Sel.
29
513-522
2016
Scheffersomyces stipitis (P34736), Scheffersomyces stipitis
Affaticati, P.E.; Dai, S.B.; Payongsri, P.; Hailes, H.C.; Tittmann, K.; Dalby, P.A.
Structural analysis of an evolved transketolase reveals divergent binding modes
Sci. Rep.
6
35716
2016
Escherichia coli (P27302), Escherichia coli
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