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(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
(E,Z,Z,Z)-8-hydroxy-5,9,11,14-eicosatetraenoic acid + [reduced NADPH-hemoprotein reductase] + O2
?
-
CYP4F2
-
-
?
(Z12(13))-epoxyoctadec-(Z9)-enoic acid + [reduced NADPH-hemoprotein reductase] + O2
?
-
-
-
-
?
(Z12(13))-epoxyoctadec-Z9-enoic acid + [reduced NADPH-hemoprotein reductase] + O2
?
-
-
-
-
?
(Z9(10))-epoxyoctadec-(Z12)-enoic acid + [reduced NADPH-hemoprotein reductase] + O2
?
-
-
-
-
?
(Z9(10))-epoxyoctadec-Z12-enoic acid + [reduced NADPH-hemoprotein reductase] + O2
?
-
-
-
-
?
(Z9(10))-epoxyoctadecanoic acid + NADPH + O2
?
-
omega-hydroxylation activity and weak (omega-1)-hydroxylation activity
-
-
?
12-hydroxy-5,8,10,14-eicosatetraenoic acid + [reduced NADPH-hemoprotein reductase] + O2
?
12-hydroxyeicosatetraenoic acid + [reduced NADPH-hemoprotein reductase] + O2
?
-
CYP4F3A
-
-
?
12-hydroxystearate + [reduced NADPH-hemoprotein reductase] + O2
?
-
-
-
-
?
20-hydroxy-leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
?
-
CYP4F3
-
-
?
20-hydroxy-leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
? + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
5-deoxy-leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
5-deoxy-20-hydroxy-leukotriene B4 + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
5-epi-leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
5-epi-20-hydroxy-leukotriene B4 + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
5-hydroxy-6,8,11,14-eicosatetraenoic acid + [reduced NADPH-hemoprotein reductase] + O2
?
-
CYP4F3
-
-
?
6-trans-12-epi-leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
6-trans-12-epi-20-hydroxy-leukotriene B4 + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
6-trans-leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
?
9,11-diazo-15-deoxy-prostaglandin H2 + [reduced NADPH-hemoprotein reductase] + O2
?
-
CYP4F8
-
-
?
9,11-epoxymethano-prostaglandin H2 + [reduced NADPH-hemoprotein reductase] + O2
?
-
CYP4F8
-
-
?
alpha-tocopherol + [reduced NADPH-hemoprotein reductase] + O2
alpha-13'-hydroxy-tocopherol + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
alpha-tocotrienol + [reduced NADPH-hemoprotein reductase] + O2
?
-
-
-
-
?
arachidonate + [reduced NADPH-hemoprotein reductase] + O2
20-hydroxy-5,8,11,14-eicosatetraenoic acid + [oxidized NADPH-hemoprotein reductase] + H2O
arachidonic acid + [reduced NADPH-hemoprotein reductase] + O2
18(R)-hydroxyarachidonate + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
arachidonic acid + [reduced NADPH-hemoprotein reductase] + O2
?
-
-
-
?
delta-tocopherol + [reduced NADPH-hemoprotein reductase] + O2
delta-13'-hydroxy-tocopherol + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
delta-tocotrienol + [reduced NADPH-hemoprotein reductase] + O2
?
-
-
-
-
?
gamma-tocopherol + [reduced NADPH-hemoprotein reductase] + O2
13'-hydroxy-gamma-tocopherol + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
gamma-tocotrienol + [reduced NADPH-hemoprotein reductase] + O2
?
-
-
-
-
?
leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
20-hydroxy-leukotriene B4 + [oxidized NADPH-hemoprotein reductase] + H2O
leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
?
-
induction of in all-trans-retinoic acid-treated HL60 cells
-
-
?
lipoxin A4 + [reduced NADPH-hemoprotein reductase] + O2
?
lipoxin B4 + [reduced NADPH-hemoprotein reductase] + O2
?
prostaglandin A1 + [reduced NADPH-hemoprotein reductase] + O2
20-hydroxy-prostaglandin A1 + [oxidized NADPH-hemoprotein reductase] + H2O
prostaglandin H1 + [reduced NADPH-hemoprotein reductase] + O2
19-hydroxy-prostaglandin H1 + [oxidized NADPH-hemoprotein reductase] + H2O
-
CYP4F8
-
-
?
prostaglandin H2 + [reduced NADPH-hemoprotein reductase] + O2
19-hydroxy-prostaglandin H2 + [oxidized NADPH-hemoprotein reductase] + H2O
-
CYP4F8
-
-
?
additional information
?
-
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
inactivation of leukotriene B4, a mediator of inflammation
390064, 390065, 390066, 390067, 390068, 390069, 390071, 390072, 390073, 390074, 390075 -
-
?
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
LTB4 inactivation, in vivo inhibition of CYP4F18 results in a marked increase in calcium flux and a 220% increases in the chemotactic response of mouse polymorphonuclear leukocytes to LTB4
-
-
?
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
inactivation of leukotriene B4, a mediator of inflammation
-
-
?
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
inactivation of leukotriene B4, a mediator of inflammation
-
-
?
12-hydroxy-5,8,10,14-eicosatetraenoic acid + [reduced NADPH-hemoprotein reductase] + O2
?
-
-
-
-
?
12-hydroxy-5,8,10,14-eicosatetraenoic acid + [reduced NADPH-hemoprotein reductase] + O2
?
-
CYP4F2
-
-
?
6-trans-leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
?
-
-
-
-
?
6-trans-leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
?
-
CYP4F2
-
-
?
6-trans-leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
?
-
CYP4F3
-
-
?
6-trans-leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
?
-
CYP4F3A
-
-
?
arachidonate + [reduced NADPH-hemoprotein reductase] + O2
20-hydroxy-5,8,11,14-eicosatetraenoic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
arachidonate + [reduced NADPH-hemoprotein reductase] + O2
20-hydroxy-5,8,11,14-eicosatetraenoic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
very poor substrate
-
-
?
arachidonate + [reduced NADPH-hemoprotein reductase] + O2
20-hydroxy-5,8,11,14-eicosatetraenoic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
the enzyme is the principal arachidonate omega-hydroxylase in liver, CYP4F2
-
-
?
leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
CYP4F3A is expressed in human leukocytes and catalyzes the omega-hydroxylation of LTB4
-
-
?
leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
CYP4F3A catalyzes the omega-hydroxylation of LTB4
-
-
?
leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
20-hydroxy-leukotriene B4 + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
20-hydroxy-leukotriene B4 + [oxidized NADPH-hemoprotein reductase] + H2O
-
leukotriene B4 is identical with (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate
390064, 390065, 390066, 390067, 390068, 390069, 390071, 390072, 390073, 390074, 390075 -
-
?
leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
20-hydroxy-leukotriene B4 + [oxidized NADPH-hemoprotein reductase] + H2O
-
the enzyme plays a critical role in regulating the biological effect of leukotriene B4, CYP4F3
-
-
?
leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
20-hydroxy-leukotriene B4 + [oxidized NADPH-hemoprotein reductase] + H2O
-
yielding omega-COOH-leukotriene B4 via omega-hydroxy-leukotriene B4 and omega-CHO-leukotriene B4, CYP4F3
-
-
?
leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
20-hydroxy-leukotriene B4 + [oxidized NADPH-hemoprotein reductase] + H2O
-
all recombinant proteins generate product I from leukotriene B4, which in all cases is indistinguishable from the 20-hydroxy-leukotriene B4 reference compound assayed under similar conditions. CYP4F3A is the most efficient leukotriene B4 20-hydroxylase. CYP4F3A and 4F3B generate a secondary product, which is 20-COOH leukotriene B4 derived from 20-hydroxy-leukotriene B4. CYP4F12 is least efficient, generating several additional products. Product I derived from CYP4F3A and that from epidermal keratinocytes are identical to the 20-hydroxy-leukotriene B4 reference compound
-
-
?
leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
20-hydroxy-leukotriene B4 + [oxidized NADPH-hemoprotein reductase] + H2O
leukotriene B4 is identical with (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate
-
-
?
leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
20-hydroxy-leukotriene B4 + [oxidized NADPH-hemoprotein reductase] + H2O
-
leukotriene B4 is identical with (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate
-
-
?
leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
20-hydroxy-leukotriene B4 + [oxidized NADPH-hemoprotein reductase] + H2O
-
leukotriene B4 is identical with (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate
-
-
?
lipoxin A4 + [reduced NADPH-hemoprotein reductase] + O2
?
-
-
-
-
?
lipoxin A4 + [reduced NADPH-hemoprotein reductase] + O2
?
-
CYP4F3 preferentially omega-jydroxylates lipoxin B4 over lipoxin A4
-
-
?
lipoxin A4 + [reduced NADPH-hemoprotein reductase] + O2
?
-
no omega-hydroxylation of LXB4, CYP4F2
-
-
?
lipoxin A4 + [reduced NADPH-hemoprotein reductase] + O2
?
-
CYP4F3A
-
-
?
lipoxin B4 + [reduced NADPH-hemoprotein reductase] + O2
?
-
-
-
-
?
lipoxin B4 + [reduced NADPH-hemoprotein reductase] + O2
?
-
CYP4F3 preferentially omega-jydroxylates lipoxin B4 over lipoxin A4
-
-
?
prostaglandin A1 + [reduced NADPH-hemoprotein reductase] + O2
20-hydroxy-prostaglandin A1 + [oxidized NADPH-hemoprotein reductase] + H2O
recombinant CYP4F14
-
-
?
prostaglandin A1 + [reduced NADPH-hemoprotein reductase] + O2
20-hydroxy-prostaglandin A1 + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
additional information
?
-
-
overview, stereochemical requirement for substrate specificity
-
-
?
additional information
?
-
-
recombinant protein CYP4F2
-
-
?
additional information
?
-
-
recombinant protein CYP4F3, wide substrate specificity
-
-
?
additional information
?
-
-
CYP4F3B and CYP4F2 may function collaboratively as 20-HETE synthetase as well as omega-hydroxylases for leukotiene b4 and other lipoxygenase-dependent eicosanoids in human liver and other tissues
-
-
?
additional information
?
-
-
no activity with 20-hydroxy-leukotriene B4 and lipoxin B4
-
-
?
additional information
?
-
cytochrome P450 4F2 gene encodes for the major CYP enzyme responsible for the synthesis of 20-hydroxyeicosatetraenoic acid in the human kidney
-
-
?
additional information
?
-
-
cytochrome P450 4F2 gene encodes for the major CYP enzyme responsible for the synthesis of 20-hydroxyeicosatetraenoic acid in the human kidney
-
-
?
additional information
?
-
-
leukotriene B4 and arachidonate omega-hydroxylase activities are both CYP4F2-catalyzed in the liver, overview
-
-
?
additional information
?
-
-
CYP4F3A also catalyzes the omega-hydroxylation of epoxyeicosatrieonic acids
-
-
?
additional information
?
-
recombinant protein CYP4F14
-
-
?
additional information
?
-
-
recombinant protein CYP4F14
-
-
?
additional information
?
-
-
CYP4F18 is a critical protein in the regulation of LTB4 metabolism, the enzyme is active in down-regulation of responses to leukotriene B4, i.e. LTB4, leukotriene B4 is a potent chemoattractant for polymorphonuclear leukocytes and other cells, overview
-
-
?
additional information
?
-
-
lipopolysaccharide treatament suppresses CYP4F4 and upregulates CYP4F5 mRNA expression in rat liver whereas renal CYP4Fs are essentially unchanged. BaSO4 treatment, in contrast, increases both hepatic and renal CYP4F expression levels
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
arachidonate + [reduced NADPH-hemoprotein reductase] + O2
20-hydroxy-5,8,11,14-eicosatetraenoic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
the enzyme is the principal arachidonate omega-hydroxylase in liver, CYP4F2
-
-
?
leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
20-hydroxy-leukotriene B4 + [oxidized NADPH-hemoprotein reductase] + H2O
-
the enzyme plays a critical role in regulating the biological effect of leukotriene B4, CYP4F3
-
-
?
leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
?
-
induction of in all-trans-retinoic acid-treated HL60 cells
-
-
?
additional information
?
-
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
inactivation of leukotriene B4, a mediator of inflammation
390064, 390065, 390066, 390067, 390068, 390069, 390071, 390072, 390073, 390074, 390075 -
-
?
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
LTB4 inactivation, in vivo inhibition of CYP4F18 results in a marked increase in calcium flux and a 220% increases in the chemotactic response of mouse polymorphonuclear leukocytes to LTB4
-
-
?
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
inactivation of leukotriene B4, a mediator of inflammation
-
-
?
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
inactivation of leukotriene B4, a mediator of inflammation
-
-
?
leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
leukotriene B4 + [reduced NADPH-hemoprotein reductase] + O2
(6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
-
CYP4F3A is expressed in human leukocytes and catalyzes the omega-hydroxylation of LTB4
-
-
?
additional information
?
-
-
CYP4F3B and CYP4F2 may function collaboratively as 20-HETE synthetase as well as omega-hydroxylases for leukotiene b4 and other lipoxygenase-dependent eicosanoids in human liver and other tissues
-
-
?
additional information
?
-
cytochrome P450 4F2 gene encodes for the major CYP enzyme responsible for the synthesis of 20-hydroxyeicosatetraenoic acid in the human kidney
-
-
?
additional information
?
-
-
cytochrome P450 4F2 gene encodes for the major CYP enzyme responsible for the synthesis of 20-hydroxyeicosatetraenoic acid in the human kidney
-
-
?
additional information
?
-
-
leukotriene B4 and arachidonate omega-hydroxylase activities are both CYP4F2-catalyzed in the liver, overview
-
-
?
additional information
?
-
-
CYP4F18 is a critical protein in the regulation of LTB4 metabolism, the enzyme is active in down-regulation of responses to leukotriene B4, i.e. LTB4, leukotriene B4 is a potent chemoattractant for polymorphonuclear leukocytes and other cells, overview
-
-
?
additional information
?
-
-
lipopolysaccharide treatament suppresses CYP4F4 and upregulates CYP4F5 mRNA expression in rat liver whereas renal CYP4Fs are essentially unchanged. BaSO4 treatment, in contrast, increases both hepatic and renal CYP4F expression levels
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
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