1.2.1.3: aldehyde dehydrogenase (NAD+)

This is an abbreviated version!
For detailed information about aldehyde dehydrogenase (NAD+), go to the full flat file.

Word Map on EC 1.2.1.3

Reaction

an aldehyde
+
NAD+
+
H2O
=
a carboxylate
+
NADH
+
H+

Synonyms

ADH, AdhE, AHD-M1, ALD1A1, ALD4, ALDDH, aldehyde dehydrogenase, aldehyde dehydrogenase (NAD), aldehyde dehydrogenase 1, aldehyde dehydrogenase 1A1, aldehyde dehydrogenase 1A3, aldehyde dehydrogenase 1B1, aldehyde dehydrogenase 2, aldehyde dehydrogenase 3A1, aldehyde dehydrogenase 7A1, aldehyde dehydrogenase class 1, aldehyde dehydrogenase type 2, Aldehyde dehydrogenase [NAD+], Aldehyde dehydrogenase, cytosolic, Aldehyde dehydrogenase, microsomal, aldehyde dehydrogenase-2, aldehyde dehydrogenase7, aldehyde:NAD+ oxidoreductase, ALDH, ALDH 2, ALDH I, ALDH II, ALDH-2, ALDH-E1, ALDH-E2, ALDH1, ALDH1-NL, ALDH1A1, Aldh1a2, Aldh1a3, Aldh1a7, Aldh1b1, ALDH2, ALDH2(1), ALDH2(2), ALDH2(3), ALDH22A1, ALDH2B8, ALDH2C4, ALDH3A1, ALDH3A2, Aldh3b1, ALDH3H1, ALDH5A, ALDH7, Aldh7a1, Aldh8a1, ALDHI, ALDHX, ALHDII, Allergen Alt a 10, aryl-aldehyde dehydrogenases, BADH, benzaldehyde dehydrogenase, Brassica turgor-responsive/drought-induced gene 26 protein, Bt-Aldh, Btg-26, class 1 aldehyde dehydrogenase, class 2 aldehyde dehydrogenase, class I ALDH, CoA-independent aldehyde dehydrogenase, coniferyl-aldehyde dehydrogenase, Cphy_1178, ETA-crystallin, FeaB-K-12, gamma-aminobutyraldehyde dehydrogenase, hALDH2, irreversible NAD+-dependent aldehyde dehydrogenase, K(+)-ACDH, K(+)-activated acetaldehyde dehydrogenase, KGSADH, m-methylbenzaldehyde dehydrogenase, Matured fruit 60 kDa protein, MF-60, Mg(2+)-ACDH, Mg(2+)-activated acetaldehyde dehydrogenase, mitochondrial aldehyde dehydrogenase, NAD+-dependent aldehyde dehydrogenase, NAD+-dependent ALDH, NAD+-linked aldehyde dehydrogenase, NAD+-pimelic semialdehyde-dependent aldehyde dehydrogenase, NAD+-specific ALDH, NAD-aldehyde dehydrogenase, NAD-dependent 4-hydroxynonenal dehydrogenase, NAD-dependent aldehyde dehydrogenase, NAD-linked aldehyde dehydrogenase, Non-lens ALDH1, p-ALDH2, P51, phenylacetaldehyde dehydrogenase, PhnN, phnY, phosphonoacetaldehyde dehydrogenase, phosphonoacetaldehyde oxidase, PM-ALDH9, PnAA dehydrogenase, propionaldehyde dehydrogenase, PuuC, R-aminobutyraldehyde dehydrogenase, RALDH, RALDH(II), RalDH1, Retinal dehydrogenase, retinal dehydrogenase type I, sALDH, salvery aldehyde dehydrogenase, ThnG, Turgor-responsive protein 26G, yALDH, YneI

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.3 aldehyde dehydrogenase (NAD+)

Molecular Weight

Molecular Weight on EC 1.2.1.3 - aldehyde dehydrogenase (NAD+)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
16200
non-denaturing PAGE
40000
-
SDS-PAGE
47430
-
deduced from amino acid sequence; electrospray mass spectrometry
48000
-
4 * 48000, SDS-PAGE
50000
50390
-
calculated from sequence of cDNA
51000
-
x * 51000, exists as large polymeric aggregates, SDS-PAGE
51300
-
4 * 51300, calculated from amino acid sequence
51500
-
4 * 51500, SDS-PAGE
52000
52600
-
4 * 52600, isoenzyme ALDH1, SDS-PAGE; 4 * 52600, isoenzyme ALDH2, SDS-PAGE
53000
53300
-
isoform ALDH1, calculated from amino acid sequence
53800
-
two-dimensional gel-electrophoresis
53886
-
8 * 53886, calculated from amino acid sequence
54200
54340
-
x * 54340, calculation from nucleotide sequence
54400
-
4 * 54400
54800
-
4 * 54800, isoenzyme 1, SDS-PAGE
55000
55076
-
x * 55076, His-tagged enzyme, calculated from amino acid sequence
55100
-
x * 55100, His-tagged enzyme, SDS-PAGE
55400
-
isoform ALDH2, calculated from amino acid sequence
55450
-
MALDI-TOF mass spectrometry
55600
-
4 * 55600, recombinant enzyme plus 13 additional residues from the pRSF Duct-1 vector, SDS-PAGE
56000
56400
-
SDS-PAGE
56500
4 * 56500, MALDI-TOF mass spectrometry; 4 * 56500, MALDI-TOF mass spectrometry
56532
-
4 * 56532, calculated from amino acid sequence
57000
58000
60000
62400
-
x * 62400, ESI-MS
66000
-
isoform ALDH22A1, calculated from amino acid sequence
85000
-
2 * 85000, GFP-tagged enzyme, SDS-PAGE
112000
-
gel filtration
114000
-
equilibrium sedimentation
115000
-
gel filtration
157600
-
sedimentation equilibrium analysis, and analytical ultracentifugation
160000
-
gel-filtration
170000
191300
A9KN57
native mass spectrometry
198000
-
equilibrium sedimentation
200000
204000
-
isoenzyme ALDH-II, gel filtration
205000
-
mitochondrial enzyme, gel filtration
208000 - 210000
-
isoenzyme I, non-denaturing PAGE
210000
-
gel filtration
212000
-
cytoplasmic enzyme, gel filtration
216000
220000
224000
-
gel filtration
225000
226000
MALDI-TOF mass spectrometry; MALDI-TOF mass spectrometry
230000
234000
-
isoenzyme ALDH-I, gel filtration
236000
-
isoenzyme III, non-denaturing PAGE
237000
-
membrane-bound isoenzyme ALDH, gel filtration
240000
-
isoenzyme F2
245000
250000
-
mitochondrial isoenzyme II, microsomal isoenzyme I and II, gel filtration
320000
-
enzyme I, gel filtration
370000
-
gel filtration in presence of detergents
440000
-
minor band, gel filtration
additional information
-
formation of large aggregates in absence of detergent