2.4.1.155: alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase This is an abbreviated version! For detailed information about alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase, go to the full flat file .
Reaction
UDP-N-acetyl-alpha-D-glucosamine +
beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein] =
UDP +
beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein]
Synonyms acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-alpha-mannoside beta1-6-UDP-N-acetylglucosamine:alpha-mannoside-beta1,6 N-acetylglucosaminyltransferase, alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetylglucosaminyltransferase, alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase, alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase, beta N-acetylglucosaminyltransferase V, beta-1,6-N-acetylglucosaminyltransferase V, beta1, 6-N-acetylglucosaminyltransferase V, beta1,6-N-acetylglucosaminyltransferase, beta1,6-N-acetylglucosaminyltransferase V, beta1,6-N-acetylglucosaminyltransferase-V, Glc-NAcT-V, GlcNAcT-V, GlcNAcTase-V, glycosyltransferase, GnT-IV, GnT-IX, GnT-V, GnT-Va, GnT-VB, Golgi beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase V, Golgi UCD-GlcNAc:N-acetylglucosaminyltransferase 5, mannoside acetylglucosaminyltransferase 5, Mgat5, N-acetylglucosaminyltransferase V, N-acetylglucosaminyltransferase Va, N-acetylglucosaminyltransferase-V, N-acetylglucosaminyltransferase-Va, N-acetylglucosaminyltransferase-Vb, N-acetylglucsaminyltransferase V, UDP-N-acetylglucosamine:a-mannoside beta-1,6-N-acetylglucosaminyltransferase
ECTree
Source Tissue
Source Tissue on EC 2.4.1.155 - alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
mouse mammary tumor cell line
brenda
-
melanotic hybrid cell
brenda
-
melanotic hybrid cell
brenda
-
-
brenda
-
observed in 6/28 cases
brenda
-
-
brenda
-
-
brenda
-
native BHK-21/c13 cells, cells transformed with Rous sarcoma virus, i.e. RS-BHK-cells, and lectin-resistant cell-lines LP 1.6 and 3.3
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
of the embryo
brenda
-
brenda
-
brenda
-
-
brenda
-
brenda
-
brenda
-
brenda
-
brenda
-
brenda
-
-
brenda
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
endometrial endometrioid adenocarcinoma cell
brenda
-
-
brenda
-
-
brenda
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
oberserved in 10/23 cases
brenda
immunohistochemic analysis of 313 clinical samples, overview
brenda
-
-
brenda
-
brenda
-
-
brenda
-
-
brenda
-
testicular germ cell
brenda
-
of the adult
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
brenda
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
brenda
-
higher expression of GnT-V is correlated with a favorable prognosis for neuroblastoma patients. GnT-V may cause these tumors to regress by increasing their susceptibility to apoptosis
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
observed in 66/68 cases
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
of the embryo
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
non-tumor tissue shows strong expression of MGAT5, immunohistochemic analysis
brenda
-
brenda
-
-
brenda
-
-
brenda
-
UtSMC, CC-2562
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
epithelial and metastatic
brenda
-
-
brenda
-
brenda
-
-
brenda
the cells show lower enzyme activity
brenda
-
-
brenda
-
brenda
-
-
brenda
-
primary
brenda
-
-
brenda
-
brenda
-
-
brenda
-
brenda
the cells show lower enzyme activity
brenda
-
-
brenda
-
-
brenda
-
of the embryo
brenda
-
-
brenda
-
-
brenda
-
brenda
-
-
brenda
-
-
brenda
-
brenda
-
QC, small lung cancer cell line
brenda
-
-
brenda
-
-
brenda
-
brenda
-
brenda
-
parental mouse melanoma cell S91 6neo
brenda
-
-
brenda
-
brenda
-
-
brenda
-
localized in the trophoblast layer. Both protein expression and the enzyme activity of GnT-V in first trimester placentas are higher than those at term. These results suggest that GnT-V would contribute to placentation in the early phase of pregnancy, possibly regulating the process of invasion of trophoblast cells
brenda
-
-
brenda
-
of the embryo
brenda
-
of the embryo
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
-
brenda
-
brenda
-
-
brenda
additional information
-
macrophage fusion hybrids with Cloudman S91 mouse melanoma cells
brenda
additional information
-
not expressed in normal thyroid tissue
brenda
additional information
quantitative enzyme expression analysis in cancer cells, overview
brenda
additional information
CNE-2 cells express 7.5fold and 2.30fold higher levels of GnT-V mRNA and protein than HNE-1 cells, and CNE-1 cells express 1.41fold and 1.36fold higher levels of GnT-V mRNA and protein than HNE-1 cells
brenda
additional information
transcriptome analysis. Overexpression of the MGAT5 gene has been found in various tumor cells and tissues
brenda
additional information
-
transcriptome analysis. Overexpression of the MGAT5 gene has been found in various tumor cells and tissues
brenda