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1.14.14.83: geraniol 8-hydroxylase

This is an abbreviated version!
For detailed information about geraniol 8-hydroxylase, go to the full flat file.

Word Map on EC 1.14.14.83

Reaction

geraniol
+
[reduced NADPH-hemoprotein reductase]
 +
O2
=
(6E)-8-hydroxygeraniol
 +
[oxidized NADPH-hemoprotein reductase]
 +
H2O

Synonyms

10-hydroxygeraniol oxidoreductase, CPR I, Cr10HGO, CYP76B10, CYP76B6, CYP76B6 protein, CYP76F45, EC 1.14.13.152, G10H, G8H, geraniol 10-hydroxylase, geraniol-10-hydroxylase, monoterpene hydroxylase, PgCYP76C9, PgG10H

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.83 geraniol 8-hydroxylase

Expression

Expression on EC 1.14.14.83 - geraniol 8-hydroxylase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
alkaloid induction medium induces the enzyme, overview
-
artemisinic acid is able to upregulate the transcriptions of geraniol 10-hydroxylase
effect of differential T-DNA transfer on transcript accumulation of MIA biosynthetic pathway genes, expression of gene g10h is 15 to 130fold increased, overview
-
expression is induced by camptothecin
-
expression is induced by fungal elicitor and methyl jasmonate
G10H expression, recombinant in Escherichia coli, is upregulated by methyljasmonate 6-36 h after treatment
G10H is repressed by ketonazole
-
methyljasmonate induces CYP76B10 expression
negative transcriptional regulation of geraniol 10-hydroxylase by calmodulin isozymes CAM1 and CAM2, overview
-
significant upregulation in salicylic acid treatment (foliar application of 0.01 and 0.1 mM salicylic acid). Upregulation can result in a higher production rate of vinblastine and vincristine alkaloids
the calmodulins CAM1 and CAM2 are required for monoterpene indole alkaloid biosynthesis in Catharanthus roseus cells by acting on regulation of expression of genes encoding enzymes that catalyse early steps of MIA biosynthesis, such as 1-deoxy-D-xylulose 5-phosphate reductoisomerase and geraniol 10-hydroxylase
-
the expression of PgG10H is differentially induced in ginseng, not only during Pseudomonas syringae infection and wounding but also after exposure to methyl jasmonate and salt stress
-
the stress hormone methyljasmonate strongly induces G10h gene expression coordinately with other terpenoid indole alkaloid biosynthesis genes in Catharanthus roseus cell culture
-
the transcription level of gene g10h is increased 15 to 130fold by integration of T-DNA in host plant genome from root inducing Ri plasmid of Agrobacterium rhizogenes for induction of hariry root growth in second metabolite production, expression analysis in root clone CP68. Also the transcription of other genes involved in the monoterpene indole alkaloid biosynthetic pathway is altered, overview
-
tissue-specific expression pattern and expression of PgG10H in response to various biotic and abiotic stresses
-
transcript levels of tryptophan decarboxylase, geraniol-10-hydroxylase, secologanin synthase, strictosidine synthase, desacetoxyvindoline-4-hydroxylase and deacetylvindoline-4-O-acetyltransferase are significantly up-regulated by salicylic acid treatments
upregulated in plants inoculated with endophytes
various hormones and elicitors upregulate G10H and the monoterpene alkaloid biosynthesis pathways. G10H activity is induced by phenobarbital
-