1.8.4.11: peptide-methionine (S)-S-oxide reductase

This is an abbreviated version!
For detailed information about peptide-methionine (S)-S-oxide reductase, go to the full flat file.

Reaction

L-methionine (S)-sulfoxide
+
thioredoxin
=
L-methionine
+
thioredoxin disulfide
+
H2O

Synonyms

ecdysone-induced protein 28/29 kDa, FMsr, LMJF_07_1140, methionine S-oxide reductase (S-form oxidizing), methionine sulfoxide reductase, methionine sulfoxide reductase A, methionine sulfoxide reductases A, methionine sulfoxide-S-reductase, methionine sulphoxide reductase, methionine sulphoxide reductase A, methionine-S-sulfoxide reductase, MetSO-L12 reductase, More, mrsA, MSR, MSR10, MSR180, MsrA, MSRA-1, MsrA/B, MsrA/MsrB, MSRA2, MSRA4, MsrABTk, MsrBA, Peptide Met(O) reductase, peptide methionine S-sulfoxide reductase, peptide methionine sulfoxide reductase, peptide methionine sulfoxide reductase A, peptide methionine sulfoxide reductase type A, peptide methionine sulphoxide reductase, peptide-methionine (S)-S-oxide reductase, peptide-methionine sulfoxide reductase, PilA, PilB, PilB protein, PMSR, PMSRA, protein-methionine-S-oxide-reductase, sulindac reductase

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.4 With a disulfide as acceptor
                1.8.4.11 peptide-methionine (S)-S-oxide reductase

KM Value

KM Value on EC 1.8.4.11 - peptide-methionine (S)-S-oxide reductase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1.1 - 2.12
9-fluorenylmethyl chloroformate-labeled L-methionine-(S)-S-oxide
0.197
Calmodulin
-
myristoylated enzyme, in 20 mM Tris-HCl, pH 7.5, 1 mM CaCl2, at 37C
1.18
dabsyl L-methionine-(S)-sulfoxide
pH 7.4, 37C, recombinant enzyme
0.14 - 1.03
dabsyl-L-methionine (S)-S-oxide
0.34 - 4.3
dabsyl-L-methionine-(S)-S-oxide
4 - 10.2
dabsylated L-methionine (S)-sulfoxide
0.84 - 15
dithiothreitol
0.25 - 0.27
glutaredoxin 2
-
9
L-methionine (R,S)-sulfoxide
-
MsrB activity of PILB, pH 8.0, 25C
0.044 - 19
L-methionine (S)-sulfoxide
0.00322 - 0.19
thioredoxin
0.013 - 0.033
tryparedoxin I
-
additional information
additional information
-