EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.21 | aldose reductase |
RAW-264.7 cell |
- |
738833 |
1.1.1.21 | aldose reductase |
RAW-264.7 cell |
inhibition or RNA interference ablation of aldose reductase suppresses lipopolysaccharide-stimulated production of nitric oxide and over-expression of inducible nitric oxide synthase. Inhibition also prevents the lipopolysaccaride-induced apoptosis, cell cycle arrest, activation of caspase-3, downregulation of Bcl-xl and up-regulation of Bax and Bak in macrophages |
686857 |
1.1.1.21 | aldose reductase |
RAW-264.7 cell |
macrophage cell line |
669503 |
1.1.1.284 | S-(hydroxymethyl)glutathione dehydrogenase |
RAW-264.7 cell |
- |
704528 |
1.13.11.33 | arachidonate 15-lipoxygenase |
RAW-264.7 cell |
- |
-, 743816 |
1.14.11.68 | [histone H3]-trimethyl-L-lysine27 demethylase |
RAW-264.7 cell |
- |
753165, 755190 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
RAW-264.7 cell |
- |
-, 696643, 763831 |
1.14.13.9 | kynurenine 3-monooxygenase |
RAW-264.7 cell |
- |
765669 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
RAW-264.7 cell |
- |
684920, 685498, 686078, 688061, 688160, 688881, 704854, 734381 |
1.14.16.5 | alkylglycerol monooxygenase |
RAW-264.7 cell |
- |
726881 |
1.14.19.77 | plasmanylethanolamine desaturase |
RAW-264.7 cell |
- |
756070 |
1.14.99.38 | cholesterol 25-monooxygenase |
RAW-264.7 cell |
- |
699414 |
1.14.99.66 | [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase |
RAW-264.7 cell |
- |
753659 |
1.17.3.2 | xanthine oxidase |
RAW-264.7 cell |
a mouse monocyte-macrophage cell line, ATCC TIB-71 |
686866 |
1.2.1.4 | aldehyde dehydrogenase (NADP+) |
RAW-264.7 cell |
murine macrophages |
673477 |
1.3.1.24 | biliverdin reductase |
RAW-264.7 cell |
- |
698922 |
1.6.1.2 | NAD(P)+ transhydrogenase (Re/Si-specific) |
RAW-264.7 cell |
- |
724953 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
RAW-264.7 cell |
- |
687451 |
2.1.1.320 | type II protein arginine methyltransferase |
RAW-264.7 cell |
- |
756077 |
2.1.1.360 | [histone H3]-lysine79 N-trimethyltransferase |
RAW-264.7 cell |
- |
753191 |
2.3.1.108 | alpha-tubulin N-acetyltransferase |
RAW-264.7 cell |
- |
736872 |
2.3.1.26 | sterol O-acyltransferase |
RAW-264.7 cell |
- |
702039 |
2.3.2.5 | glutaminyl-peptide cyclotransferase |
RAW-264.7 cell |
- |
672393 |
2.7.1.137 | phosphatidylinositol 3-kinase |
RAW-264.7 cell |
- |
688988 |
2.7.1.153 | phosphatidylinositol-4,5-bisphosphate 3-kinase |
RAW-264.7 cell |
- |
709980 |
2.7.1.91 | sphingosine kinase |
RAW-264.7 cell |
- |
674843, 706578 |
2.7.10.1 | receptor protein-tyrosine kinase |
RAW-264.7 cell |
- |
703732 |
2.7.10.2 | non-specific protein-tyrosine kinase |
RAW-264.7 cell |
- |
692647, 693466, 694202 |
2.7.11.10 | IkappaB kinase |
RAW-264.7 cell |
- |
662155, 662570, 723569 |
2.7.11.10 | IkappaB kinase |
RAW-264.7 cell |
macrophage cell line |
671920 |
2.7.11.10 | IkappaB kinase |
RAW-264.7 cell |
monocyte/macrophage cell line |
662731 |
2.7.11.13 | protein kinase C |
RAW-264.7 cell |
virus-induced macrophage cell line |
660959 |
2.7.11.22 | cyclin-dependent kinase |
RAW-264.7 cell |
- |
708041 |
2.7.11.24 | mitogen-activated protein kinase |
RAW-264.7 cell |
- |
691878, 703166 |
2.7.11.31 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase |
RAW-264.7 cell |
- |
-, 703618 |
2.7.12.1 | dual-specificity kinase |
RAW-264.7 cell |
- |
761591 |
2.7.7.15 | choline-phosphate cytidylyltransferase |
RAW-264.7 cell |
- |
702429 |
2.7.7.6 | DNA-directed RNA polymerase |
RAW-264.7 cell |
- |
738954 |
2.7.7.86 | cyclic GMP-AMP synthase |
RAW-264.7 cell |
- |
738791 |
3.1.1.4 | phospholipase A2 |
RAW-264.7 cell |
- |
691109 |
3.1.1.5 | lysophospholipase |
RAW-264.7 cell |
isoform lysophospholipase I only |
714838 |
3.1.1.79 | hormone-sensitive lipase |
RAW-264.7 cell |
- |
690756 |
3.1.13.4 | poly(A)-specific ribonuclease |
RAW-264.7 cell |
mouse macrophage cell line |
690354 |
3.1.3.16 | protein-serine/threonine phosphatase |
RAW-264.7 cell |
- |
729950 |
3.1.3.4 | phosphatidate phosphatase |
RAW-264.7 cell |
- |
691109 |
3.1.3.48 | protein-tyrosine-phosphatase |
RAW-264.7 cell |
- |
692163 |
3.1.3.66 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase |
RAW-264.7 cell |
- |
751928 |
3.1.4.11 | phosphoinositide phospholipase C |
RAW-264.7 cell |
- |
678448 |
3.1.4.12 | sphingomyelin phosphodiesterase |
RAW-264.7 cell |
- |
714052 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
RAW-264.7 cell |
- |
750479 |
3.1.4.4 | phospholipase D |
RAW-264.7 cell |
- |
708072 |
3.1.4.50 | glycosylphosphatidylinositol phospholipase D |
RAW-264.7 cell |
macrophage cell line |
646477 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
RAW-264.7 cell |
- |
750479 |
3.2.2.6 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase |
RAW-264.7 cell |
- |
750282 |
3.4.11.22 | aminopeptidase I |
RAW-264.7 cell |
- |
717825 |
3.4.17.22 | metallocarboxypeptidase D |
RAW-264.7 cell |
- |
683703 |
3.4.21.107 | peptidase Do |
RAW-264.7 cell |
- |
753322 |
3.4.21.20 | cathepsin G |
RAW-264.7 cell |
monocyte/macrophage cell line |
691629 |
3.4.21.37 | leukocyte elastase |
RAW-264.7 cell |
- |
698263, 707071 |
3.4.21.41 | complement subcomponent C1r |
RAW-264.7 cell |
C1r mRNA expression is significantly increased in RAW 264.7 cells in which low-density lipoprotein receptorrelated protein 1 is silenced |
696932 |
3.4.21.53 | Endopeptidase La |
RAW-264.7 cell |
- |
752805 |
3.4.21.69 | Protein C (activated) |
RAW-264.7 cell |
- |
753065, 753066 |
3.4.21.7 | plasmin |
RAW-264.7 cell |
- |
717866 |
3.4.22.1 | cathepsin B |
RAW-264.7 cell |
- |
-, 698050, 709979 |
3.4.22.27 | cathepsin S |
RAW-264.7 cell |
- |
753968 |
3.4.22.36 | caspase-1 |
RAW-264.7 cell |
- |
669224 |
3.4.22.38 | cathepsin K |
RAW-264.7 cell |
- |
697010 |
3.4.22.55 | caspase-2 |
RAW-264.7 cell |
- |
713348, 731559 |
3.4.22.62 | caspase-9 |
RAW-264.7 cell |
caspase-9, which is activated by infection with virulent Mycobacterium tuberculosis, contributes to the inhibition of necrosis of the infected host cells, through suppression of generation of intracellular reactive oxygen species |
680139 |
3.4.22.B74 | SENP6 peptidase |
RAW-264.7 cell |
- |
752453 |
3.4.24.17 | stromelysin 1 |
RAW-264.7 cell |
- |
735131 |
3.4.24.35 | gelatinase B |
RAW-264.7 cell |
- |
-, 709950, 717577 |
3.4.24.B4 | matrix metalloproteinase-13 |
RAW-264.7 cell |
- |
712131 |
3.5.1.23 | ceramidase |
RAW-264.7 cell |
- |
733093 |
3.5.1.60 | N-(long-chain-acyl)ethanolamine deacylase |
RAW-264.7 cell |
- |
734845 |
3.5.3.1 | arginase |
RAW-264.7 cell |
- |
667160 |
3.5.3.15 | protein-arginine deiminase |
RAW-264.7 cell |
- |
719902 |
3.5.4.6 | AMP deaminase |
RAW-264.7 cell |
a macrophage-like cell line sensitive to anthrax lethal toxin, i.e. LeTx, induced death |
720959 |
3.6.1.5 | apyrase |
RAW-264.7 cell |
- |
699181 |
3.6.5.2 | small monomeric GTPase |
RAW-264.7 cell |
- |
-, 734361, 757678 |
3.6.5.5 | dynamin GTPase |
RAW-264.7 cell |
- |
696022 |
4.1.1.17 | ornithine decarboxylase |
RAW-264.7 cell |
- |
708244 |
4.1.1.19 | arginine decarboxylase |
RAW-264.7 cell |
- |
749140 |
4.1.1.22 | histidine decarboxylase |
RAW-264.7 cell |
- |
690778 |
4.2.99.18 | DNA-(apurinic or apyrimidinic site) lyase |
RAW-264.7 cell |
- |
713769 |
4.3.2.1 | argininosuccinate lyase |
RAW-264.7 cell |
- |
-, 730344 |
4.4.1.1 | cystathionine gamma-lyase |
RAW-264.7 cell |
- |
708059 |
4.6.1.1 | adenylate cyclase |
RAW-264.7 cell |
a macrophage-like cell line |
693116 |
5.3.4.1 | protein disulfide-isomerase |
RAW-264.7 cell |
- |
691923 |
5.3.99.3 | prostaglandin-E synthase |
RAW-264.7 cell |
- |
691241 |
6.1.1.15 | proline-tRNA ligase |
RAW-264.7 cell |
- |
-, 745867 |
6.1.1.17 | glutamate-tRNA ligase |
RAW-264.7 cell |
- |
-, 745867 |
6.3.2.2 | glutamate-cysteine ligase |
RAW-264.7 cell |
- |
690677, 745805 |
7.1.1.9 | cytochrome-c oxidase |
RAW-264.7 cell |
- |
692264 |
7.2.2.9 | P-type Cu2+ transporter |
RAW-264.7 cell |
- |
712400 |