2.5.1.18: glutathione transferase
This is an abbreviated version!
For detailed information about glutathione transferase, go to the full flat file.
Word Map on EC 2.5.1.18
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2.5.1.18
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catalase
-
dismutase
-
sod
-
pull-down
-
malondialdehyde
-
carcinogenesis
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detoxify
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hepatocytes
-
smoke
-
isoenzymes
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cyp1a1
-
smoking
-
case-control
-
electrophilic
-
epoxide
-
aquatic
-
wistar
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genotoxic
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insecticide
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chemopreventive
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gill
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hepatocarcinogenesis
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acetylcholinesterase
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polycyclic
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pesticide
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hydroperoxide
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thiobarbituric
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hepatotoxicity
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tbars
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ache
-
albino
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metallothioneins
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cigarette
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benzoapyrene
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phenobarbital
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drug-metabolizing
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preneoplastic
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alt
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aflatoxin
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gssg
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hepatoprotective
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schistosoma
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comet
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carboxylesterase
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mussel
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udp-glucuronosyltransferase
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methylation-specific
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gsh-px
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organophosphate
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drug development
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medicine
-
cyp2d6
-
biotechnology
-
analysis
- 2.5.1.18
- catalase
- dismutase
- sod
-
pull-down
- malondialdehyde
- carcinogenesis
-
detoxify
- hepatocytes
-
smoke
- isoenzymes
- cyp1a1
-
smoking
-
case-control
-
electrophilic
- epoxide
-
aquatic
- wistar
-
genotoxic
-
insecticide
-
chemopreventive
- gill
-
hepatocarcinogenesis
- acetylcholinesterase
-
polycyclic
-
pesticide
- hydroperoxide
-
thiobarbituric
-
hepatotoxicity
-
tbars
-
ache
-
albino
- metallothioneins
-
cigarette
-
benzoapyrene
- phenobarbital
-
drug-metabolizing
-
preneoplastic
-
alt
- aflatoxin
- gssg
-
hepatoprotective
- schistosoma
- comet
- carboxylesterase
- mussel
-
udp-glucuronosyltransferase
-
methylation-specific
- gsh-px
-
organophosphate
- drug development
- medicine
- cyp2d6
- biotechnology
- analysis
Reaction
Synonyms
2-hydroxychromene-2-carboxylic acid isomerase, 26GST, adGSTD4-4, agGSTe2, allergen Der p 2, allergen Der p 8, alpha class glutathione transferase, Alpha class GST, alpha GST, alpha-class glutathione transferase, asGST5.5, AtGSTF2, AtuGSTH1-1, BaeAB, beta-etherase, bmGSTD, BphK, CgGSTM1, CgGSTM2, cGST, Chi class GST, Chi GST, class mu glutathione S-transferase, delta class glutathione transferase, delta-class glutathione S-transferase, Delta-class glutathione transferase, EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14, EC 4.4.1.7, EGST, epsilon class GST, Epsilon glutathione S-transferase, Epsilon glutathione transferase, Epsilon GST, epsilon-class glutathione S-transferase, epsilon-class glutathione transferase, GHR, glutathione S-alkyl transferase, glutathione S-aralkyltransferase, glutathione S-aryltransferase, glutathione S-transferase, glutathione S-transferase 2, glutathione S-transferase A1-1, glutathione S-transferase A3-3, glutathione S-transferase AdFSTD3-3, glutathione S-transferase I, glutathione S-transferase omega 1, glutathione S-transferase omega 2, glutathione S-transferase P1-1, glutathione S-transferase pi, glutathione S-transferase Pi-1, glutathione S-transferase X, glutathione transferase, glutathione transferase A1-1, glutathione transferase A4-4, glutathione transferase M1-1, glutathione transferase M2-2, glutathione transferase Omega 3S, glutathione transferase omega-1, glutathione transferase P1-1, glutathione transferase Pi, glutathione transferase T1-1, glutathione transferase zeta, glutathione transferase zeta 1, glutathione transferase Zeta 1-1, glutathione transferase zeta1-1, glutathione transferase-like protein, glutathione-S-transferas, glutathione-S-transferase, glutathione-S-transferase pi, glutathione-transferase, GmGSTU4-4, GSH S-transferase, GSH transferase, GSH transferase homologue, GSH-S transferase rho, GSHTase-P, GST, GST A1-1, GST A2-2, GST A3-3, GST A4-4, GST adgstD4-4, GST alpha, GST Delta 2, GST I, GST II, GST III, GST IV, GST M1-1, GST M2-2, GST M4-4, GST M5-5, GST mu, GST O1-1, GST P1-1, GST pi, GST T1-1, GST Tau, GST Tau19, GST Z1-1, GST-1, GST-2, GST-26, GST-3, GST-Acr, GST-OCX-32, GST-T, GST-theta, GST1, GST1b, GST2, GST20, GST3, GST4, GST5, GST5118, GST7, GST83044, Gsta, GSTA1, GSTA1-1, GSTA2-2, GSTA3, GSTA3-3, GSTA4, GSTA4-4, GSTA4L, GSTA5, GSTA5-5, GSTalpha1, GSTD, GSTD1, GSTD10, GSTd14, GSTD2, GSTD4, GSTD4-4, GSTE1, GSTE2, GSTE3, GSTE4, GSTE5, GSTE6, GSTE7, GSTE8, GSTF12-1, GSTF12-2, GSTF3, GSTF5, GSTF9, GSTFuA1, GSTk, GSTK1, GSTL1, GSTL2, GSTL3, Gstm, GSTm09, GSTM1, GSTM1-1, GSTM2, GSTM2-2, GSTM3, GSTM3-3, GSTM4, GSTM4-4, GSTM5, GSTM5-5, GSTmu, GSTO, GSTO1, GSTO1-1, GSTO2, GSTO2-2, GstO2A, GstO2B, GSTO3, GSTO3S, GSTO4, GSTO7, GSTP, GSTP 1-1, GSTP-1, GSTP1, GSTP1-1, Gstr1, GSTrho, GSTS, GSTS1, GSTS1-1, GSTS2, GSTS3, GSTT, GSTT1, GSTT1-1, Gstt1a, GSTT2, GSTT2-2, GSTT2B-2B, GSTT4, GSTT4L, GSTU1, GSTU10, GSTU10-10, GSTU11, GSTU12, GSTU13, GSTU13-1, GSTU14, GSTU16, GSTU17, GSTU18, GSTU19, GSTU2, GSTU2-2, GSTU21, GSTU24, GSTU24-1, GSTU25, GSTU26, GSTU28, GSTU3, GSTU4, GSTU45, GSTU5, GSTU6, GSTU7, GSTU8, GSTU9, GSTZ, Gstz1, GSTZ1-1, GTT1.2, HCCA isomerase, Hematopoietic prostaglandin D synthase, hGSTA-3, hGSTA1-1, hGSTZ1-1, kappa class glutathione transferase, kappa class GSH transferase, Kappa class GST, KKSG9, lambda glutathione transferase, MAAI, MGST1, MGST2, MGST3, Mgst3a, Mgst3b, microsomal glutathione transferase 1, microsomal glutathione transferase-1, More, mtMGST1, mu class glutathione S-transferase, Mu class GST, mu glutathione transferase, Mu GST, mu-class glutathione S-transferase, mu-class glutathione S-transferase1, Mu-class GST, Mu-GST, nu-class glutathione transferase, Omega class GST, omega glutathione S-transferase, omega glutathione transferase, omega-class glutathione S-transferase, omega-class glutathione S-transferase 2, pGSTA1, phi class glutathione transferase, Pi class GST, pm-GSTR1, PmGST, PtGSTU1, PvGSTF1-1, PvGSTU2-2, PvGSTU3-3, rho class glutathione S-transferase, rho-GST, RX: glutathione R-transferase, RX:glutathione R-transferase, S-(hydroxyalkyl)glutathione lyase, Saro_2873/Saro_2872, selenium-containing glutathione transferase zeta1-1, seleno-hGSTZ1-1, SGST26.5, sigma class glutathione transferase, Sigma class GST, sigma glutathione S-transferase, sigma-class glutathione S-transferase, sigma-class GST, SIGST, Sj26GST, sjGST, sll1545, ssGST3, ssGST5, tau class glutathione S-transferase, tau class glutathione transferase, tau class GST, tau class GSTU4-4, TDR1, theta class glutathione S-transferase, theta class glutathione transferase T1-1, theta class GST, theta-class glutathione transferase, thiol-dependent reductase I, Ure2p mutant A122C, Ure2pB1, Xi class glutathione transferase, Ya-GST, YghU, zeta class glutathione S-transferase, Zeta class GST
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Turnover Number on EC 2.5.1.18 - glutathione transferase
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TURNOVER NUMBER [1/s] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.044
2-chloro-5-nitropyridine
-
25°C, 20 mM sodium phosphate buffer, pH 7.0, 0.5 mM glutathione
0.04
2-hydroxyethyl disulfide
-
pH 6.5, 37°C, recombinant AtuGSTH1-1
0.037
7-oxabicyclo[4.1.0]heptan-2-one
-
4°C, 20 mM sodium phosphate buffer, pH 6.5, 0.5 mM glutathione
1.03
acetyl-gamma-Glu-Cys-Gly
mutant enzyme I104V/A113V, at pH 7.4 and 25°C
0.000000451
alpha-O-(beta-methylumbelliferyl)acetovanillone
wild type enzyme, pH and temperature not specified in the publication
39
L-gamma-glutamyl-S-[2-hydroxy-3-methoxy-1-(4-methoxyphenyl)-3-oxopropyl]-L-cysteinylglycine
-
25°C, 20 mM sodium phosphate buffer, pH 7.0, 0.5 mM glutathione
0.63
methyl 3-(4-methoxyphenyl)oxirane-2-carboxylate
-
25°C, 20 mM sodium phosphate buffer, pH 7.0, 0.5 mM glutathione
180
S-phenylacetylglutathione
isoform GSTO4, at pH 6.5 and 20°C
19
trans-o-hydroxybenzylidene pyruvic acid
-
pH 7.0, 25°C, recombinant enzyme
0.19
(+)-2-bromo-3-(4-nitrophenyl)propanoic acid
-
pH 7.4, 37°C, mutant enzyme R175A of glutathione transferase Zeta 1c-1c
0.55
(+)-2-bromo-3-(4-nitrophenyl)propanoic acid
-
pH 7.4, 37°C, enzyme variant glutathione transferase Zeta 1d-1d
0.59
(+)-2-bromo-3-(4-nitrophenyl)propanoic acid
-
pH 7.4, 37°C, enzyme variant glutathione transferase Zeta 1c-1c
0.61
(+)-2-bromo-3-(4-nitrophenyl)propanoic acid
-
pH 7.4, 37°C, mutant enzyme R175K of glutathione transferase Zeta 1c-1c
0.82
(+)-2-bromo-3-(4-nitrophenyl)propanoic acid
-
pH 7.4, 37°C, enzyme variant glutathione transferase Zeta 1b-1b
1
(+)-2-bromo-3-(4-nitrophenyl)propanoic acid
-
pH 7.4, 37°C, mutant enzyme S15A of glutathione transferase Zeta 1c-1c
2.55
(+)-2-bromo-3-(4-nitrophenyl)propanoic acid
-
pH 7.4, 37°C, mutant enzyme C16A of glutathione transferase Zeta 1c-1c
13
(+)-2-bromo-3-(4-nitrophenyl)propanoic acid
-
pH 7.4, 37°C, enzyme variant glutathione transferase Zeta 1a-1a
2.7
(R)-styrene-7,8-oxide
-
mutant enzyme G112C, at 30°C in 250 mM Tris-HCl buffer, pH 7.2
4.4
(R)-styrene-7,8-oxide
-
mutant enzyme I10C, at 30°C in 250 mM Tris-HCl buffer, pH 7.2
4.8
(R)-styrene-7,8-oxide
-
wild type enzyme, at 30°C in 250 mM Tris-HCl buffer, pH 7.2
0.83
(R,R)-1-phenylpropylene oxide
-
mutant enzyme I10C, at 30°C in 250 mM Tris-HCl buffer, pH 7.2
4.6
(R,R)-1-phenylpropylene oxide
-
mutant enzyme G112C, at 30°C in 250 mM Tris-HCl buffer, pH 7.2
17.7
(R,R)-1-phenylpropylene oxide
-
wild type enzyme, at 30°C in 250 mM Tris-HCl buffer, pH 7.2
0.37
(R,R)-trans-stilbene oxide
-
wild type enzyme I10C, at 30°C in 250 mM Tris-HCl buffer, pH 7.2
1.3
(R,R)-trans-stilbene oxide
-
wild type enzyme G112C, at 30°C in 250 mM Tris-HCl buffer, pH 7.2
7.7
(R,R)-trans-stilbene oxide
-
wild type enzyme, at 30°C in 250 mM Tris-HCl buffer, pH 7.2
2.3
(S)-styrene-7,8-oxide
-
mutant enzyme I10C, at 30°C in 250 mM Tris-HCl buffer, pH 7.2
3.2
(S)-styrene-7,8-oxide
-
mutant enzyme G112C, at 30°C in 250 mM Tris-HCl buffer, pH 7.2
8.4
(S)-styrene-7,8-oxide
-
wild type enzyme, at 30°C in 250 mM Tris-HCl buffer, pH 7.2
1.1
(S,S)-1-phenylpropylene oxide
-
wild type enzyme I10C, at 30°C in 250 mM Tris-HCl buffer, pH 7.2
2.4
(S,S)-1-phenylpropylene oxide
-
wild type enzyme G112C, at 30°C in 250 mM Tris-HCl buffer, pH 7.2
9
(S,S)-1-phenylpropylene oxide
-
wild type enzyme, at 30°C in 250 mM Tris-HCl buffer, pH 7.2
0.07
(S,S)-trans-stilbene oxide
-
wild type enzyme I10C, at 30°C in 250 mM Tris-HCl buffer, pH 7.2
0.2
(S,S)-trans-stilbene oxide
-
wild type enzyme G112C, at 30°C in 250 mM Tris-HCl buffer, pH 7.2
0.46
(S,S)-trans-stilbene oxide
-
wild type enzyme, at 30°C in 250 mM Tris-HCl buffer, pH 7.2
0.035
1,3-Bis-(2-chloroethyl)-1-nitrosourea
-
pH 7.4, 37°C, recombinant wild-type isozyme GST-T1-1
2.3
1,3-Bis-(2-chloroethyl)-1-nitrosourea
-
pH 7.4, 37°C, recombinant wild-type isozyme GST-T1-1
3.6
1,3-Bis-(2-chloroethyl)-1-nitrosourea
-
pH 7.4, 37°C, recombinant mutant F2:1215
3.6
1,3-Bis-(2-chloroethyl)-1-nitrosourea
-
pH 7.4, 37°C, recombinant mutant F2:1215
0.0678
1-chloro-2,4-dinitrobenzene
mutant enzyme N22A, pH and temperature not specified in the publication
0.0897
1-chloro-2,4-dinitrobenzene
pH 6.5, 30°C, recombinant GSTU4-4 mutant S13A
0.1
1-chloro-2,4-dinitrobenzene
-
isoform GTT1.2, at pH 7.5, temperature not specified in the publication
0.18
1-chloro-2,4-dinitrobenzene
wild type enzyme, pH and temperature not specified in the publication
0.27
1-chloro-2,4-dinitrobenzene
mutant enzyme S11A, at pH 8.0 and 30°C
0.33
1-chloro-2,4-dinitrobenzene
mutant enzyme F119A, at pH 8.0 and 30°C
0.53
1-chloro-2,4-dinitrobenzene
-
pH 6.5, 37°C, recombinant AtuGSTH1-1
0.54
1-chloro-2,4-dinitrobenzene
mutant enzyme F212E, in 0.1 M phosphate buffer pH 6.5
0.99
1-chloro-2,4-dinitrobenzene
recombinant His-tagged mutant F108G, pH and temperature not specified in the publication
1.07
1-chloro-2,4-dinitrobenzene
mutant enzyme V54A, at pH 8.0 and 30°C
1.1
1-chloro-2,4-dinitrobenzene
mutant enzyme H106A, at 25°C, in 100 mM phosphate buffer (pH 6.5)
1.27
1-chloro-2,4-dinitrobenzene
mutant enzyme H52A, at pH 8.0 and 30°C
1.415
1-chloro-2,4-dinitrobenzene
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU7, at pH 6.5 and 25°C
1.45
1-chloro-2,4-dinitrobenzene
pH 6.5, 30°C, recombinant GSTU4-4 mutant D48A
1.5
1-chloro-2,4-dinitrobenzene
-
isoform Ure2pB1, at pH 7.5, temperature not specified in the publication
1.6
1-chloro-2,4-dinitrobenzene
mutant enzyme C10S, at 25°C, in 100 mM phosphate buffer (pH 6.5)
1.934
1-chloro-2,4-dinitrobenzene
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU12, at pH 6.5 and 25°C
2.061
1-chloro-2,4-dinitrobenzene
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU8, at pH 6.5 and 25°C
2.08
1-chloro-2,4-dinitrobenzene
isoform GSTO7, at pH 6.5 and 20°C
2.14
1-chloro-2,4-dinitrobenzene
mutant enzyme T174A, in 0.1 M phosphate buffer pH 6.5
2.48
1-chloro-2,4-dinitrobenzene
pH 6.5, 30°C, recombinant wild-type GSTU4-4
2.67
1-chloro-2,4-dinitrobenzene
wild type enzyme, at pH 8.0 and 30°C
2.67
1-chloro-2,4-dinitrobenzene
mutant enzyme E66A, at pH 8.0 and 30°C
2.89
1-chloro-2,4-dinitrobenzene
isoform GSTU16, pH not specified in the publication, at 30°C
3
1-chloro-2,4-dinitrobenzene
mutant enzyme S67A, at pH 8.0 and 30°C
3.17
1-chloro-2,4-dinitrobenzene
mutant enzyme R68A, at pH 8.0 and 30°C
3.55
1-chloro-2,4-dinitrobenzene
mutant enzyme F212H, in 0.1 M phosphate buffer pH 6.5
4.62
1-chloro-2,4-dinitrobenzene
-
at pH 7.0, temperature not specified in the publication
4.8
1-chloro-2,4-dinitrobenzene
mutant enzyme H106F, at 25°C, in 100 mM phosphate buffer (pH 6.5)
5.3
1-chloro-2,4-dinitrobenzene
isoform GSTU45, pH not specified in the publication, at 30°C
5.9
1-chloro-2,4-dinitrobenzene
pH 6.5, 30°C, recombinant GSTU4-4 mutant P49A
6
1-chloro-2,4-dinitrobenzene
-
recombinant His6-tagged isozyme GSTE8-8, pH and temperature not specified in the publication
6.056
1-chloro-2,4-dinitrobenzene
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU1, at pH 6.5 and 25°C
6.44
1-chloro-2,4-dinitrobenzene
mutant enzyme F212Y, in 0.1 M phosphate buffer pH 6.5
7
1-chloro-2,4-dinitrobenzene
-
recombinant His6-tagged isozyme GSTE7-7, pH and temperature not specified in the publication
7.782
1-chloro-2,4-dinitrobenzene
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU5, at pH 6.5 and 25°C
8
1-chloro-2,4-dinitrobenzene
recombinant His-tagged mutant R113A, pH and temperature not specified in the publication
8.85
1-chloro-2,4-dinitrobenzene
mutant enzyme F212W, in 0.1 M phosphate buffer pH 6.5
9.1
1-chloro-2,4-dinitrobenzene
wild type enzyme, at 25°C, in 100 mM phosphate buffer (pH 6.5)
10
1-chloro-2,4-dinitrobenzene
-
recombinant His6-tagged isozyme GSTE1-1, pH and temperature not specified in the publication
11
1-chloro-2,4-dinitrobenzene
-
recombinant His6-tagged isozyme GSTE2-2 from strain NO, pH and temperature not specified in the publication
11.7
1-chloro-2,4-dinitrobenzene
recombinant His-tagged wild-type enzyme, pH and temperature not specified in the publication
12.6
1-chloro-2,4-dinitrobenzene
mutant enzyme Y215S, in 0.1 M phosphate buffer pH 6.5
12.8
1-chloro-2,4-dinitrobenzene
mutant enzyme F216A, in 0.1 M phosphate buffer pH 6.5
13.9
1-chloro-2,4-dinitrobenzene
mutant enzyme Y215A, in 0.1 M phosphate buffer pH 6.5
14.9
1-chloro-2,4-dinitrobenzene
mutant enzyme F212A, in 0.1 M phosphate buffer pH 6.5
14.948
1-chloro-2,4-dinitrobenzene
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU13, at pH 6.5 and 25°C
16.183
1-chloro-2,4-dinitrobenzene
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU10, at pH 6.5 and 25°C
17
1-chloro-2,4-dinitrobenzene
mutant enzyme Y215E, in 0.1 M phosphate buffer pH 6.5
18.7
1-chloro-2,4-dinitrobenzene
mutant enzyme F212L, in 0.1 M phosphate buffer pH 6.5
20.5
1-chloro-2,4-dinitrobenzene
mutant enzyme R214A, in 0.1 M phosphate buffer pH 6.5
20.7
1-chloro-2,4-dinitrobenzene
mutant enzyme Y215H, in 0.1 M phosphate buffer pH 6.5
21.06
1-chloro-2,4-dinitrobenzene
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU9, at pH 6.5 and 25°C
22.472
1-chloro-2,4-dinitrobenzene
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU11, at pH 6.5 and 25°C
23
1-chloro-2,4-dinitrobenzene
-
recombinant His6-tagged isozyme GSTE2-2 from strain PMD-R, pH and temperature not specified in the publication
23
1-chloro-2,4-dinitrobenzene
-
recombinant His6-tagged isozyme GSTE4-4, pH and temperature not specified in the publication
24.482
1-chloro-2,4-dinitrobenzene
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU4, at pH 6.5 and 25°C
25.1
1-chloro-2,4-dinitrobenzene
recombinant detagged wild-type enzyme, pH and temperature not specified in the publication
26.4
1-chloro-2,4-dinitrobenzene
mutant enzyme Q112A, in 0.1 M phosphate buffer pH 6.5
26.5
1-chloro-2,4-dinitrobenzene
wild type enzyme, in 0.1 M phosphate buffer pH 6.5
28.819
1-chloro-2,4-dinitrobenzene
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU3, at pH 6.5 and 25°C
29.42
1-chloro-2,4-dinitrobenzene
recombinant mutant S22A, pH 6.5, temperature not specified in the publication
35.7
1-chloro-2,4-dinitrobenzene
mutant enzyme Y215F, in 0.1 M phosphate buffer pH 6.5
38.18
1-chloro-2,4-dinitrobenzene
-
isoform GSTFuA1, at pH 7.5, temperature not specified in the publication
41.823
1-chloro-2,4-dinitrobenzene
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU14, at pH 6.5 and 25°C
46
1-chloro-2,4-dinitrobenzene
-
recombinant His6-tagged isozyme GSTE3-3, pH and temperature not specified in the publication
51
1-chloro-2,4-dinitrobenzene
-
recombinant His6-tagged isozyme GSTE5-5, pH and temperature not specified in the publication
55.8
1-chloro-2,4-dinitrobenzene
mutant enzyme C10A, at 25°C, in 100 mM phosphate buffer (pH 6.5)
82
1-chloro-2,4-dinitrobenzene
-
pH 7.4, 30°C, purified recombinant isozyme P1-1
87.87
1-chloro-2,4-dinitrobenzene
wild type enzyme, at pH 7.5, temperature not specified in the publication
100.25
1-chloro-2,4-dinitrobenzene
mutant enzyme F136A, at pH 7.5, temperature not specified in the publication
103.3
1-chloro-2,4-dinitrobenzene
-
pH 7.4, 30°C, purified recombinant isozyme P1-1
112.987
1-chloro-2,4-dinitrobenzene
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU6, at pH 6.5 and 25°C
187
1-chloro-2,4-dinitrobenzene
-
4°C, 20 mM sodium phosphate buffer, pH 6.5, 0.5 mM glutathione
2286
1-chloro-2,4-dinitrobenzene
-
pH 6.5, 25°C, recombinant catalytically active monoclonal antibody fragment ScFv2F3
0.257
4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole
wild type enzyme, at 25°C, pH not specified in the publication
0.266
4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole
mutant enzyme N109A, at 25°C, pH not specified in the publication
0.277
4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole
mutant enzyme Y113A, at 25°C, pH not specified in the publication
0.512
4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole
mutant enzyme F116A, at 25°C, pH not specified in the publication
0.809
4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole
mutant enzyme M17A, at 25°C, pH not specified in the publication
0.999
4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole
mutant enzyme W161A, at 25°C, pH not specified in the publication
1.573
4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole
mutant enzyme F162A, at 25°C, pH not specified in the publication
1.75
4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole
mutant enzyme L112A, at 25°C, pH not specified in the publication
0.00000163
4-methylumbelliferyl acetate
mutant enzyme N24A, pH and temperature not specified in the publication
0.00333
4-methylumbelliferyl acetate
wild type enzyme, pH and temperature not specified in the publication
0.083
4-nitrobenzyl chloride
mutant enzyme Y12C, pH and temperature not specified in the publication
0.27
4-nitrobenzyl chloride
wild type enzyme, pH and temperature not specified in the publication
0.29
4-nitrophenyl butyrate
recombinant mutant S22A, pH 6.5, temperature not specified in the publication
27.6
4-nitrophenyl butyrate
recombinant wild-type, pH 6.5, temperature not specified in the publication
0.000146
5-chloromethylfluorescein diacetate
mutant enzyme Y46A, pH and temperature not specified in the publication
0.000321
5-chloromethylfluorescein diacetate
mutant enzyme N24A, pH and temperature not specified in the publication
0.000714
5-chloromethylfluorescein diacetate
wild type enzyme, pH and temperature not specified in the publication
0.000906
5-chloromethylfluorescein diacetate
mutant enzyme N22A, pH and temperature not specified in the publication
0.25
allyl-isothiocyanate
isoform GSTU45, pH not specified in the publication, at 30°C
3.6
allyl-isothiocyanate
isoform GSTU16, pH not specified in the publication, at 30°C
0.14
beta-(2-methoxyphenoxy)-gamma-hydroxypropiovanillone
Q2G4B4; Q2G4B5
mutant enzyme N14A, at pH 8.0 and 30°C
2.4
beta-(2-methoxyphenoxy)-gamma-hydroxypropiovanillone
Q2G4B4; Q2G4B5
mutant enzyme S15A, at pH 8.0 and 30°C
2.8
beta-(2-methoxyphenoxy)-gamma-hydroxypropiovanillone
Q2G4B4; Q2G4B5
mutant enzyme S14A, at pH 8.0 and 30°C
2.8
beta-(2-methoxyphenoxy)-gamma-hydroxypropiovanillone
Q2G4B4; Q2G4B5
mutant enzyme S14A/S15A, at pH 8.0 and 30°C
2.9
beta-(2-methoxyphenoxy)-gamma-hydroxypropiovanillone
Q2G4B4; Q2G4B5
wild type enzyme, at pH 8.0 and 30°C
0.0007
cumene hydroperoxide
mutant enzyme N24A, pH and temperature not specified in the publication
0.21
cumene hydroperoxide
wild type enzyme, pH and temperature not specified in the publication
0.27
cumene hydroperoxide
isoform GSTU45, pH not specified in the publication, at 30°C
0.58
cumene hydroperoxide
isoform GSTU16, pH not specified in the publication, at 30°C
9.03
cumene hydroperoxide
-
at pH 7.0, temperature not specified in the publication
1.26
dehydroascorbate
isoform GSTO4, at pH 6.5 and 20°C
673.7
dehydroascorbate
isoform GstO2A, at pH 7.6 and 30°C
925.2
dehydroascorbate
isoform GstO2B, at pH 7.6 and 30°C
0.2
Ethacrynic acid
mutant enzyme F212L, in 0.1 M phosphate buffer pH 6.5
0.28
Ethacrynic acid
wild type enzyme, in 0.1 M phosphate buffer pH 6.5
0.36
Ethacrynic acid
mutant enzyme Q112A, in 0.1 M phosphate buffer pH 6.5
0.38
Ethacrynic acid
mutant enzyme Y215S, in 0.1 M phosphate buffer pH 6.5
0.4
Ethacrynic acid
mutant enzyme Y215A, in 0.1 M phosphate buffer pH 6.5
0.00098
glutathione
-
with fluorodifen as cosubstrate, pH and temperature not specified in the publication
0.01
glutathione
-
pH 6.5, 25°C, recombinant enzyme, with (2Z,4E)-3-chloro-6-(3,5-dichlorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid
0.022
glutathione
mutant enzyme Y12C, pH and temperature not specified in the publication
0.04
glutathione
-
pH 6.5, 37°C, recombinant AtuGSTH1-1, with 2-hydroxyethyl disulfide
0.086
glutathione
wild type enzyme, pH and temperature not specified in the publication
0.16
glutathione
-
pH 6.5, 25°C, recombinant enzyme, with (2Z,4E)-3-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid
0.16
glutathione
-
with cumene hydroperoxide as cosubstrate, pH and temperature not specified in the publication
0.196
glutathione
mutant enzyme N109A, at 25°C, pH not specified in the publication
0.22
glutathione
mutant enzyme Y113A, at 25°C, pH not specified in the publication
0.23
glutathione
recombinant mutant S22A, pH 6.5, temperature not specified in the publication
0.24
glutathione
-
pH 6.5, 25°C, recombinant enzyme, with (2E,4Z)-5-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid
0.26
glutathione
with tert-butyl peroxide as cosubstrate, at pH 6.5 and 25°C
0.264
glutathione
wild type enzyme, at 25°C, pH not specified in the publication
0.3
glutathione
mutant enzyme C10S, at 25°C, in 100 mM phosphate buffer (pH 6.5)
0.3
glutathione
-
Ure2p mutant A122C, at 25°C and pH 8.0, in the presence of 1 mM dithiothreitol
0.322
glutathione
mutant enzyme F116A, at 25°C, pH not specified in the publication
0.387
glutathione
mutant enzyme M17A, at 25°C, pH not specified in the publication
0.421
glutathione
mutant enzyme F162A, at 25°C, pH not specified in the publication
0.53
glutathione
-
pH 6.5, 37°C, recombinant AtuGSTH1-1, with 1-chloro-2,4-dinitrobenzene
0.573
glutathione
mutant enzyme W161A, at 25°C, pH not specified in the publication
0.58
glutathione
with cumene hydroperoxide as cosubstrate, at pH 6.5 and 25°C
0.804
glutathione
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU7, at pH 6.5 and 25°C
0.946
glutathione
mutant enzyme L112A, at 25°C, pH not specified in the publication
1.1
glutathione
mutant enzyme H106A, at 25°C, in 100 mM phosphate buffer (pH 6.5)
1.13
glutathione
mutant F108G, pH and temperature not specified in the publication
1.197
glutathione
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU8, at pH 6.5 and 25°C
1.314
glutathione
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU12, at pH 6.5 and 25°C
1.42
glutathione
-
with 1-chloro-2,4-dinitrobenzene as cosubstrate, pH and temperature not specified in the publication
1.43
glutathione
-
with tert-butyl peroxide as cosubstrate, pH and temperature not specified in the publication
2.496
glutathione
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU2, at pH 6.5 and 25°C
2.65
glutathione
with 1-chloro-2,4-dinitrobenzene as cosubstrate, at pH 6.5 and 25°C
2.963
glutathione
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU4, at pH 6.5 and 25°C
3
glutathione
-
with phenethyl isothiocyanate as cosubstrate, at pH 7.0, temperature not specified in the publication
3.376
glutathione
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU5, at pH 6.5 and 25°C
4.62
glutathione
-
with 1-chloro-2,4-dinitrobenzene as cosubstrate, at pH 7.0, temperature not specified in the publication
6
glutathione
-
recombinant His6-tagged isozyme GSTE8-8, pH and temperature not specified in the publication
6.283
glutathione
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU1, at pH 6.5 and 25°C
6.8
glutathione
mutant enzyme H106F, at 25°C, in 100 mM phosphate buffer (pH 6.5)
7
glutathione
-
recombinant His6-tagged isozyme GSTE7-7, pH and temperature not specified in the publication
7.391
glutathione
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU10, at pH 6.5 and 25°C
7.564
glutathione
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU9, at pH 6.5 and 25°C
7.7
glutathione
wild type enzyme, at 25°C, in 100 mM phosphate buffer (pH 6.5)
9.03
glutathione
-
with cumene hydroperoxide as cosubstrate, at pH 7.0, temperature not specified in the publication
10
glutathione
-
recombinant His6-tagged isozyme GSTE1-1, pH and temperature not specified in the publication
11
glutathione
mutant R113A, pH and temperature not specified in the publication
11
glutathione
-
recombinant His6-tagged isozyme GSTE2-2 from strain NO, pH and temperature not specified in the publication
11.03
glutathione
recombinant wild-type, pH 6.5, temperature not specified in the publication
11.4
glutathione
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU13, at pH 6.5 and 25°C
12.281
glutathione
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU14, at pH 6.5 and 25°C
14
glutathione
wild-type enzyme, pH and temperature not specified in the publication
16.302
glutathione
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU11, at pH 6.5 and 25°C
16.483
glutathione
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU6, at pH 6.5 and 25°C
16.714
glutathione
A0A4Y5QZW9, A0A4Y5QZX0, A0A4Y5QZX2, A0A4Y5QZX3, A0A4Y5QZX9, A0A4Y5QZZ8, A0A4Y5R032, A0A4Y5R087, A0A4Y5R0B2, A0A4Y5R0C1, A0A4Y5R0K8, A0A4Y5R0L5, A0A4Y5R2M7, A0A4Y5R2N2
isoform GSTU3, at pH 6.5 and 25°C
17
glutathione
Thermosynechococcus vestitus
at 30°C in 0.1 M potassium phosphate buffer
23
glutathione
-
recombinant His6-tagged isozyme GSTE2-2 from strain PMD-R, pH and temperature not specified in the publication
23
glutathione
-
recombinant His6-tagged isozyme GSTE4-4, pH and temperature not specified in the publication
41
glutathione
mutant enzyme C10A, at 25°C, in 100 mM phosphate buffer (pH 6.5)
46
glutathione
-
recombinant His6-tagged isozyme GSTE3-3, pH and temperature not specified in the publication
51
glutathione
-
recombinant His6-tagged isozyme GSTE5-5, pH and temperature not specified in the publication
2286
glutathione
-
pH 6.5, 25°C, recombinant catalytically active monoclonal antibody fragment ScFv2F3
0.19
GSH
-
pH 7.4, 37°C, mutant enzyme R175A of glutathione transferase Zeta 1c-1c, reaction with (+)-2-bromo-3-(4-nitrophenyl)propanoic acid
0.61
GSH
-
pH 7.4, 37°C, mutant enzyme R175K of glutathione transferase Zeta 1c-1c, reaction with (+)-2-bromo-3-(4-nitrophenyl)propanoic acid
1
GSH
-
pH 7.4, 37°C, mutant enzyme S15A of glutathione transferase Zeta 1c-1c, reaction with (+)-2-bromo-3-(4-nitrophenyl)propanoic acid
2.55
GSH
-
pH 7.4, 37°C, mutant enzyme C16A of glutathione transferase Zeta 1c-1c, reaction with (+)-2-bromo-3-(4-nitrophenyl)propanoic acid
72.6
GSH
-
pH 7.4, 37°C, mutant enzyme S15A of glutathione transferase Zeta 1c-1c, reaction with maleylacetone
107
GSH
-
30°C, mutant enzyme Y108F, reaction with 1,2-epoxy-3-(p-nitrophenoxy)propane
108
GSH
-
30°C, wild-type enzyme, reaction with 1,2-epoxy-3-(p-nitrophenoxy)propane
132
GSH
-
30°C, mutant enzyme Y108A, reaction with 1,2-epoxy-3-(p-nitrophenoxy)propane
141
GSH
-
pH 7.4, 37°C, mutant enzyme C16A of glutathione transferase Zeta 1c-1c, reaction with maleylacetone
149
GSH
-
pH 7.4, 37°C, mutant enzyme R175A of glutathione transferase Zeta 1c-1c, reaction with maleylacetone
150
GSH
-
30°C, mutant enzyme Y108W, reaction with 1,2-epoxy-3-(p-nitrophenoxy)propane
368
GSH
-
pH 7.4, 37°C, mutant enzyme R175K of glutathione transferase Zeta 1c-1c, reaction with maleylacetone
464
GSH
-
pH 7.4, 37°C, glutathione transferase Zeta 1c-1c, reaction with maleylacetone
72.6
maleylacetone
-
pH 7.4, 37°C, mutant enzyme S15A of glutathione transferase Zeta 1c-1c
141
maleylacetone
-
pH 7.4, 37°C, mutant enzyme C16A of glutathione transferase Zeta 1c-1c
149
maleylacetone
-
pH 7.4, 37°C, mutant enzyme R175A of glutathione transferase Zeta 1c-1c
368
maleylacetone
-
pH 7.4, 37°C, mutant enzyme R175K of glutathione transferase Zeta 1c-1c
0.14
phenethyl isothiocyanate
isoform GSTU45, pH not specified in the publication, at 30°C
1.69
phenethyl isothiocyanate
isoform GSTO7, at pH 6.5 and 20°C
3
phenethyl isothiocyanate
-
at pH 7.0, temperature not specified in the publication
8.52
phenethyl isothiocyanate
recombinant wild-type, pH 6.5, temperature not specified in the publication
62.9
phenethyl isothiocyanate
isoform GSTU16, pH not specified in the publication, at 30°C
21.4
phenethyl-isothiocyanate
Thermosynechococcus vestitus
at 30°C in 0.1 M potassium phosphate buffer
63.4
phenethyl-isothiocyanate
-
at 30°C in 0.1 M potassium phosphate buffer
0.073
sulforaphane
isoform GSTU45, pH not specified in the publication, at 30°C
2.57
sulforaphane
isoform GSTU16, pH not specified in the publication, at 30°C
