1.2.1.4: aldehyde dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about aldehyde dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.2.1.4

Reaction

an aldehyde
+
NADP+
+
H2O
=
a carboxylate
+
NADPH
+
H+

Synonyms

AKR1A4, aldehyde dehydrogenase (NADP+), aldehyde dehydrogenase 3A1, aldehyde reductase, ALDH, ALDH1, ALDH3A1, AlDHPyr1147, dehydrogenase, aldehyde (nicotinamide adenine dinucleotide phosphate), Kvbeta2, NADP dependent aldehyde dehydrogenase, NADP-acetaldehyde dehydrogenase, NADP-dependent aldehyde dehydrogenase, Seegmiller enzyme

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.4 aldehyde dehydrogenase (NADP+)

pH Range

pH Range on EC 1.2.1.4 - aldehyde dehydrogenase (NADP+)

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5 - 9.2
-
pH 5.0: 10% of maximal activity, pH 9.2: 15% of maximal activity
6.8 - 8.7
-
about 50% of maximal activity at pH 6.8 and 8.0
8 - 11.5
-
pH 8.5: about 60% of maximal activity, pH 11.5: about 80% of maximal activity