1.2.1.4: aldehyde dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about aldehyde dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.2.1.4

Reaction

an aldehyde
+
NADP+
+
H2O
=
a carboxylate
+
NADPH
+
H+

Synonyms

AKR1A4, aldehyde dehydrogenase (NADP+), aldehyde dehydrogenase 3A1, aldehyde reductase, ALDH, ALDH1, ALDH3A1, AlDHPyr1147, dehydrogenase, aldehyde (nicotinamide adenine dinucleotide phosphate), Kvbeta2, NADP dependent aldehyde dehydrogenase, NADP-acetaldehyde dehydrogenase, NADP-dependent aldehyde dehydrogenase, Seegmiller enzyme

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.4 aldehyde dehydrogenase (NADP+)

Specific Activity

Specific Activity on EC 1.2.1.4 - aldehyde dehydrogenase (NADP+)

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.00312
-
native enzyme, with NAD+ as cofactor, pH and temperature not specified in the publication
0.00315
-
mutant enzyme A200E, with NAD+ as cofactor, pH and temperature not specified in the publication
0.0113
-
mutant enzyme A200E/V210Q, with NAD+ as cofactor, pH and temperature not specified in the publication
0.012
-
mutant enzyme A200E/V210Q, with NADP+ as cofactor, pH and temperature not specified in the publication
0.06
-
mutant enzyme A200E, with NADP+ as cofactor, pH and temperature not specified in the publication
0.853
-
wild type enzyme from cornea, using propionaldehyde and NAD+ as substrates
2
-
purified enzyme, pH 7.5, 25°C
3
-
native enzyme, with NADP+ as cofactor, pH and temperature not specified in the publication
3.43
-
wild type enzyme from cornea, using NADP+ and benzaldehyde as substrates
additional information