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isozyme UGT1A8
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low-level UGT1A5 expression
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O60656, O75310, O75795, P06133, P16662, P19224, P22309, P22310, P35503, P35504, P36537, P54855, Q6UWM9, Q9BY64, Q9HAW7, Q9HAW8, Q9HAW9, Q9Y4X1 -
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O60656, O75310, O75795, P06133, P16662, P19224, P22309, P22310, P35503, P35504, P36537, P54855, Q6UWM9, Q9BY64, Q9HAW7, Q9HAW8, Q9HAW9, Q9Y4X1 -
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androgens do not only affect their own inactivation but also influence the levels of monohydroxy-fatty acids by regulating the expression of UGT2B enzymes in an isoform-specific manner
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isozyme UGT1A9
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proximal, epithelial cells
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O60656, O75310, O75795, P06133, P16662, P19224, P22309, P22310, P35503, P35504, P36537, P54855, Q6UWM9, Q9BY64, Q9HAW7, Q9HAW8, Q9HAW9, Q9Y4X1 -
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isozyme UGT1A7
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isozyme UGT2B7
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expression level is 91% of the expression level in liver
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main expression in small intestine, colon, and adipose tissue
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isozyme UGT1A7
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obtained after in vitro fertilization with gametes from B6D2F1 hybrid mice and from embryo culture. The blastocysts express Ugt1a globally, in the cytoplasm and nuclei of all of the cells, presence of Ugt1a6 but not Ugt1a1, Ugt1a3, Ugt1a4, or Ugt1a9. The Ugt2b proteins are not detected, Immunofluorescence analysis and Western blot
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obtained after in vitro fertilization with gametes from B6D2F1 hybrid mice and from embryo culture. The blastocysts express Ugt1a globally, in the cytoplasm and nuclei of all of the cells, presence of Ugt1a6 but not Ugt1a1, Ugt1a3, Ugt1a4, or Ugt1a9. The Ugt2b proteins are not detected, Immunofluorescence analysis and Western blot
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O60656, O75310, O75795, P06133, P16662, P19224, P22309, P22310, P35503, P35504, P36537, P54855, Q6UWM9, Q9BY64, Q9HAW7, Q9HAW8, Q9HAW9, Q9Y4X1 for example in the nucleus bulbosus of the olfactory system
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mostly in the hippocampus and cerebellum
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O60656, O75310, O75795, P06133, P16662, P19224, P22309, P22310, P35503, P35504, P36537, P54855, Q6UWM9, Q9BY64, Q9HAW7, Q9HAW8, Q9HAW9, Q9Y4X1 -
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low expression level
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identification of isozyme UGT1A10 in non-malignant and malignant human breast tissues, UGT1A10 and UGT2B7 mRNAs are differentially expressed among healthy and malignant specimens, in African American women, UGT1A10 expression is significantly decreased in breast carcinomas in comparison to healthy, while among Caucasian women, overview
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UGT1A10 and UGT2B7 mRNAs are differentially expressed among healthy and malignant specimens, in African American women, UGT2B7 is significantly decreased in breast carcinomas in comparison to healthy, overview
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O60656, O75310, O75795, P06133, P16662, P19224, P22309, P22310, P35503, P35504, P36537, P54855, Q6UWM9, Q9BY64, Q9HAW7, Q9HAW8, Q9HAW9, Q9Y4X1 -
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low-level UGT1A5 expression
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low expression level
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isozyme UGT1A9
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expression level is 78% of the expression level in liver
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main expression in small intestine, colon, and adipose tissue
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isoform UGT2A1 is expressed in aerodigestive tract tissues including trachea, larynx and tonsil, and is also expressed in lung and colon. Isoform UGT2A1 exhibits highest expression in the lung, followed in decreasing order by trachea, tonsil, larynx, colon, olfactory tissue
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O60656, O75310, O75795, P06133, P16662, P19224, P22309, P22310, P35503, P35504, P36537, P54855, Q6UWM9, Q9BY64, Q9HAW7, Q9HAW8, Q9HAW9, Q9Y4X1 high expression level of UGT1A6
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O60656, O75795, P06133, P16662, P19224, P22309, P22310, P35503, P54855, Q9HAW7, Q9HAW8, Q9HAW9 -
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recombinant
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human UGT supersomes, i.e. membranes of insect cells transfected with baculovirus containing human cDNA of UGTs or microsomes of lymphoblast cells heterologously expressing human cDNA of UGT1A1
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recombinant isozyme UGT1A1
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recombinant isozyme UGT2B7
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nonhepatic UGT supersomes of 1A1, 1A3, 1A4, 1A6, 1A7, 1A8, 1A9, and 1A10
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bronchial
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mucosal epithelial layer of the gastrointestinal tract
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of renal proximal tubules
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nasal epithelium, isoform UGT2A1
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very low expression level
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isoform UGT1A7
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O60656, O75310, O75795, P06133, P16662, P19224, P22309, P22310, P35503, P35504, P36537, P54855, Q6UWM9, Q9BY64, Q9HAW7, Q9HAW8, Q9HAW9, Q9Y4X1 -
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isozymes UGT1A1, UGT1A3, UGT1A6, UGT1A8, UGT1A9, UGT1A10, and UGT2B7
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isozymes UGT1 and UGT2
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primary culture
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a low basal level of UGT1A5 expression in cultured hepatocytes. Treatment with rifampicin or 3-methylcholanthrene increases the level of UGT1A5 mRNA
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primary culture
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isozyme UGT1A1
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Q20CK6, Q20CK7, Q20CK8, Q20CK9, Q20CL0, Q20CL1, Q20CL2, Q20CL3, Q20CL4, Q20CL5, Q20CL6 -
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Q20CK6, Q20CK7, Q20CK8, Q20CK9, Q20CL0, Q20CL1, Q20CL2, Q20CL3, Q20CL4, Q20CL5, Q20CL6 isozyme UGT1A7
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Q20CK6, Q20CK7, Q20CK8, Q20CK9, Q20CL0, Q20CL1, Q20CL2, Q20CL3, Q20CL4, Q20CL5, Q20CL6 isozyme UGT1A8
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Q20CK6, Q20CK7, Q20CK8, Q20CK9, Q20CL0, Q20CL1, Q20CL2, Q20CL3, Q20CL4, Q20CL5, Q20CL6 isozyme UGT1A10A
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Q20CK6, Q20CK7, Q20CK8, Q20CK9, Q20CL0, Q20CL1, Q20CL2, Q20CL3, Q20CL4, Q20CL5, Q20CL6 isozyme UGT1A10B
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Q20CK6, Q20CK7, Q20CK8, Q20CK9, Q20CL0, Q20CL1, Q20CL2, Q20CL3, Q20CL4, Q20CL5, Q20CL6 isozyme UGT1A4
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Q20CK6, Q20CK7, Q20CK8, Q20CK9, Q20CL0, Q20CL1, Q20CL2, Q20CL3, Q20CL4, Q20CL5, Q20CL6 isozyme UGT1A5A
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Q20CK6, Q20CK7, Q20CK8, Q20CK9, Q20CL0, Q20CL1, Q20CL2, Q20CL3, Q20CL4, Q20CL5, Q20CL6 isozyme UGT1A5B
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O60656, O75310, O75795, P06133, P16662, P19224, P22309, P22310, P35503, P35504, P36537, P54855, Q6UWM9, Q9BY64, Q9HAW7, Q9HAW8, Q9HAW9, Q9Y4X1 -
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mucosa, isozymes UGT1A9 and UGT2B7
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UGT1A5 expression in various segments of the intestine, high interindividual variability in its level and distribution along the intestine
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high expression
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isozyme UGT1A1
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isozymes UGT1A9
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isozymes UGT1A9 and UGT1A1
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isoform UGT1A10, preferential formation of 4-menadiol glucuronide
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predominant expression of isoform UGT2B9
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cortex
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cortex and medulla
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isozyme UGT1A9
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isozyme UGT2B7
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isozymes UGT1A9 and UGT2B7
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isozymes UGT1 and UGT2
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with the exception of the glomerulus, Bowmans capsule, and renal vasculature, isozymes UGT1A and UGT2B7 are expressed throughout the proximal and distal convoluted tubules, the loops of Henle, and the collecting ducts. Additionally, UGT1A and UGT2B7 expression occurs in the macula densa, immunolocalization of isozymes UGT1A and UGT2B7 in the renal cortex, overview
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predominant expression of isoforms UGT2A3 and UGT2B18
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488698, 488704, 488707, 488712, 488736, 488746, 488760, 488790, 488794, 691934, 673287 brenda
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isoform UGT2A1 is expressed in aerodigestive tract tissues including trachea, larynx and tonsil, and is also expressed in lung and colon. Isoform UGT2A1 exhibits highest expression in the lung, followed in decreasing order by trachea, tonsil, larynx, colon, olfactory tissue
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488696, 488707, 488709, 488720, 488743, 488761, 488762, 488763, 488770, 488772, 488778, 488781, 488785, 488786, 488792, 488793, 488794, 488801, 657879, 658516, 658522, 658529 brenda
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694249, 703403, 703407, 703415, 719347, 719348, 719349, 719352, 720303, 720509, 721114, 735944, 756020, 756439, 756562 brenda
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O60656, O75310, O75795, P06133, P16662, P19224, P22309, P22310, P35503, P35504, P36537, P54855, Q6UWM9, Q9BY64, Q9HAW7, Q9HAW8, Q9HAW9, Q9Y4X1 -
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O60656, O75795, P06133, P16662, P19224, P22309, P22310, P35503, P54855, Q9HAW7, Q9HAW8, Q9HAW9 -
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A0A0G2JMZ5, D6RH08, O60656, P06133, P16662, P19224, P22309, P22310, P35503, Q9HAW7, Q9HAW8, Q9HAW9 -
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O60656, O75795, P06133, P16662, P19224, P22309, P22310, P35503, P35504, P36537, P54855 -
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high expression level
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low expression level
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isozyme UGT1A1
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isozyme UGT1A1 and UGT1A9
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isozyme UGT2B7
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isozymes UGT1A1, UGT1A3, UGT1A6, UGT1A9, and UGT2B7
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isozymes UGT1A9 and UGT2B7
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constitutively expressed with high interindividual variability of human liver enzyme levels is due to a number of influences, including genetic, tissue-specific, and environmental factors. Homo- and heterozygotic expression of UGT1A6 alleles markedly affects enzyme activity. HNF1 may be responsible for tissue-specific UGT1A6 expression. Multiple environmental factors controll UGT1A6 expression, including the pregnane X receptor, the constitutive androstane receptor, the aryl hydrocarbon receptor, and Nrf2, a bZIP transcription factor mediating stress responses
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isozymes UGT1 and UGT2
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low-level UGT1A5 expression
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of trangenic mice expressing the UGT1 locus of human. In maternal 14-day post-conception Tg-UGT1 mice, liver UGT1A1, UGT1A4, and UGT1A6 are induced, with the levels returning to near normal by birth. However, maternal liver UGT1A4 and UGT1A6 are dramatically elevated and maintained after birth, indicating that these proteins may play a critical role in maternal metabolism during lactation
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of transgenic mice expressing the UGT1 locus of human. In maternal 14-day post-conception Tg-UGT1 mice, liver UGT1A1, UGT1A4, and UGT1A6 are induced, with the levels returning to near normal by birth. However, maternal liver UGT1A4 and UGT1A6 are dramatically elevated and maintained after birth, indicating that these proteins may play a critical role in maternal metabolism during lactation
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expression of most isozymes
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isozyme UGT2B10 is exclusively expressed in liver
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isozyme UGT2B15
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isozyme UGT2B17
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high expression of isoforms UGT2B4 and UGT2B15
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isoform UGT1A10
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isoform UGT1A6, preferential formation of 1-menadiol glucuronide
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low expression, activity in intestinal microsomes is markedly higher than in liver microsomes
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O60656, O75310, O75795, P06133, P16662, P19224, P22309, P22310, P35503, P35504, P36537, P54855, Q6UWM9, Q9BY64, Q9HAW7, Q9HAW8, Q9HAW9, Q9Y4X1 strong expression of UGT2B4 in human fetal liver
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protein expression of UGT isozymes 1A1, 1A3, 1A4, 1A6, 1A9, 2B7, 3A1, and 3A2 using western blots from 164 healthy human liver samples, comparing expression with age and sex, relative protein levels among major human hepatic UGTs, detailed overview
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predominant expression of isoforms UGT2B19, UGT2B23, UGT2B33, UGT2B30, UGT2B20
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isoform Ugt2b36 is highly expressed in the liver
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Q20CK6, Q20CK7, Q20CK8, Q20CK9, Q20CL0, Q20CL1, Q20CL2, Q20CL3, Q20CL4, Q20CL5, Q20CL6 -
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Q20CK6, Q20CK7, Q20CK8, Q20CK9, Q20CL0, Q20CL1, Q20CL2, Q20CL3, Q20CL4, Q20CL5, Q20CL6 isozyme UGT1A1
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Q20CK6, Q20CK7, Q20CK8, Q20CK9, Q20CL0, Q20CL1, Q20CL2, Q20CL3, Q20CL4, Q20CL5, Q20CL6 isozyme UGT1A9
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Q20CK6, Q20CK7, Q20CK8, Q20CK9, Q20CL0, Q20CL1, Q20CL2, Q20CL3, Q20CL4, Q20CL5, Q20CL6 isozyme UGT1A2A
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Q20CK6, Q20CK7, Q20CK8, Q20CK9, Q20CL0, Q20CL1, Q20CL2, Q20CL3, Q20CL4, Q20CL5, Q20CL6 isozyme UGT1A6
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488695, 488696, 488697, 488698, 488700, 488701, 488703, 488704, 488706, 488707, 488710, 488711, 488715, 488716, 488717, 488718, 488719, 488720, 488721, 488723, 488725, 488727, 488730, 488732, 488733, 488734, 488735, 488736, 488737, 488738, 488739, 488740, 488744, 488745, 488746, 488748, 488749, 488750, 488752, 488756, 488758, 488762, 488764, 488771, 488773, 488779, 488790, 488792, 488793, 488794, 658529, 691045, 691935, 692039, 735776, 756511, 673287 brenda
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both the activity and mRNA expression of UG2T2B12 are decreased after initiation of hepatic regeneration and recovered completely by day 6
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both the activity and mRNA expression of UGT2B2 are decreased after initiation of hepatic regeneration and recovered completely by day 6
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expression of UGT1A5 mRNA is not altered by partial hepatectomy
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expression of UGT1A8 mRNA is not altered by partial hepatectomy
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expression of UGT2B8 mRNA is down-regulated during hepatic regeneration
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mRNA expression of UGT1A2 is increased during hepatic regeneration
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mRNA expression of UGT1A3 is increased during hepatic regeneration
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the activity of UGT1A1 is decreased 24 h and 6 days after partial hepatectomy and recovered by day 14. The mRNA expression of UGT1A1 is also decreased 24 h and 6 days after initiation of regeneration and returns to normal level by day 14
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the activity of UGT2B1 is decreased 24 h after partial hepatectomy. The mRNA expression of UGT2B1 is also decreased 24 h after regeneration and returns back to normal level by day 6
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expression of most isozymes
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UGT activities in the microminipig are similar to those in the minipig
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low activity, UGT2B4
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low activity, UGT2B7
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UGT2B10
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UGT2B17
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intestinal cell line
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low expression level
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isoform UGT2A1 is expressed in aerodigestive tract tissues including trachea, larynx and tonsil, and is also expressed in lung and colon. Isoform UGT2A1 exhibits highest expression in the lung, followed in decreasing order by trachea, tonsil, larynx, colon, olfactory tissue
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floor of mouth, high expression level
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floor of mouth, very low expression level
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intestinal, isozymes UGT1A9 and UGT2B7
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mucosal epithelial layer of the gastrointestinal tract
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predominant expression of isoform UGT2A1
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predominant expression of isoform UGT2A2
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isozyme UGT2B15, immunohistochemic analysis of isozyme distribution, UGT2B15 occurs in luminal epithelial cells, overview
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isozyme UGT2B17, immunohistochemic analysis of isozyme distribution, overview
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isozyme UGT2B15
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isozyme UGT2B17
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expression level is 160% of the expression level in liver
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isoforms UGT1A8 and UGT1A10
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main expression in small intestine, colon, and adipose tissue. Activity in intestinal microsomes is markedly higher than in liver microsomes
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O60656, O75310, O75795, P06133, P16662, P19224, P22309, P22310, P35503, P35504, P36537, P54855, Q6UWM9, Q9BY64, Q9HAW7, Q9HAW8, Q9HAW9, Q9Y4X1 high expression level of UGT1A6
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low expression
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isozyme UGT1A10
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isozyme UGT1A7
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isozyme UGT1A8
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isozymes UGT1A7 and UGT1A8
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O60656, O75310, O75795, P06133, P16662, P19224, P22309, P22310, P35503, P35504, P36537, P54855, Q6UWM9, Q9BY64, Q9HAW7, Q9HAW8, Q9HAW9, Q9Y4X1 high expression level of UGT1A6
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low expression
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very low expression level
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isoform UGT2A1 is expressed in aerodigestive tract tissues including trachea, larynx and tonsil, and is also expressed in lung and colon. Isoform UGT2A1 exhibits highest expression in the lung, followed in decreasing order by trachea, tonsil, larynx, colon, olfactory tissue
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low expression
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isoform UGT2A1 is expressed in aerodigestive tract tissues including trachea, larynx and tonsil, and is also expressed in lung and colon. Isoform UGT2A1 exhibits highest expression in the lung, followed in decreasing order by trachea, tonsil, larynx, colon, olfactory tissue
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isozyme UGT1A1
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isozyme UGT2B7
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additional information
wide tissue distribution
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additional information
wide tissue distribution
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additional information
wide tissue distribution
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additional information
wide tissue distribution
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additional information
tissue distribution and expression patterns of isozymes UGT1A1, and UGT1A7-10
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additional information
tissue distribution and expression patterns of isozymes UGT1A1, and UGT1A7-10
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additional information
tissue distribution and expression patterns of isozymes UGT1A1, and UGT1A7-10
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additional information
tissue distribution and expression patterns of isozymes UGT1A1, and UGT1A7-10
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additional information
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tissue distribution and expression patterns of isozymes UGT1A1, and UGT1A7-10
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tissue distribution and expression patterns of isozymes, overview
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additional information
tissue distribution and expression patterns of isozymes, overview
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additional information
tissue distribution and expression patterns of isozymes, overview
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tissue distribution and expression patterns of isozymes, overview
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tissue distribution and expression patterns of isozymes, overview
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tissue-specific serotonin glucuronidation activity
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tissue-specific serotonin glucuronidation activity
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no activity in prostate epithelial cells, UGT2B10
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no activity in prostate epithelial cells, UGT2B10
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additional information
no activity in prostate epithelial cells, UGT2B10
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additional information
no activity in prostate epithelial cells, UGT2B10
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additional information
no activity in prostate epithelial cells, UGT2B10
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additional information
no activity in prostate epithelial cells, UGT2B10
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additional information
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no activity in prostate epithelial cells, UGT2B10
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no activity in prostate epithelial cells, UGT2B17
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no activity in prostate epithelial cells, UGT2B17
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additional information
no activity in prostate epithelial cells, UGT2B17
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additional information
no activity in prostate epithelial cells, UGT2B17
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additional information
no activity in prostate epithelial cells, UGT2B17
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additional information
no activity in prostate epithelial cells, UGT2B17
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additional information
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no activity in prostate epithelial cells, UGT2B17
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no activity in prostate epithelial cells, UGT2B4
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additional information
no activity in prostate epithelial cells, UGT2B4
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additional information
no activity in prostate epithelial cells, UGT2B4
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additional information
no activity in prostate epithelial cells, UGT2B4
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additional information
no activity in prostate epithelial cells, UGT2B4
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additional information
no activity in prostate epithelial cells, UGT2B4
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additional information
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no activity in prostate epithelial cells, UGT2B4
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no activity in prostate epithelial cells, UGT2B7
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no activity in prostate epithelial cells, UGT2B7
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no activity in prostate epithelial cells, UGT2B7
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additional information
no activity in prostate epithelial cells, UGT2B7
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additional information
no activity in prostate epithelial cells, UGT2B7
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additional information
no activity in prostate epithelial cells, UGT2B7
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additional information
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no activity in prostate epithelial cells, UGT2B7
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additional information
isozyme UGT2A3 expression analysis in human tissues, overview
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isozyme UGT2A3 expression analysis in human tissues, overview
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no activity of isoform UGT1A6 in the jejunum
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additional information
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no expression in brain
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additional information
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no expression of isoform UGT2A1 in breast, whole brain, pancreas, prostate, kidney, liver or esophagus
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additional information
in children aged below 18 years, UGT1A4 and UGT1A9 protein expressions is significantly correlated, but not for adults aged above 18 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT1A6 and UGT1A9 correlates in the entire sample population
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additional information
in children aged below 18 years, UGT1A4 and UGT1A9 protein expressions is significantly correlated, but not for adults aged above 18 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT1A6 and UGT1A9 correlates in the entire sample population
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additional information
in children aged below 18 years, UGT1A4 and UGT1A9 protein expressions is significantly correlated, but not for adults aged above 18 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT1A6 and UGT1A9 correlates in the entire sample population
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additional information
in children aged below 18 years, UGT1A4 and UGT1A9 protein expressions is significantly correlated, but not for adults aged above 18 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT1A6 and UGT1A9 correlates in the entire sample population
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additional information
in children aged below 18 years, UGT1A4 and UGT1A9 protein expressions is significantly correlated, but not for adults aged above 18 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT1A6 and UGT1A9 correlates in the entire sample population
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additional information
in children aged below 18 years, UGT1A4 and UGT1A9 protein expressions is significantly correlated, but not for adults aged above 18 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT1A6 and UGT1A9 correlates in the entire sample population
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additional information
in children aged below 18 years, UGT1A4 and UGT1A9 protein expressions is significantly correlated, but not for adults aged above 18 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT1A6 and UGT1A9 correlates in the entire sample population
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additional information
in children aged below 18 years, UGT1A4 and UGT1A9 protein expressions is significantly correlated, but not for adults aged above 18 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT1A6 and UGT1A9 correlates in the entire sample population
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additional information
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in children aged below 18 years, UGT1A4 and UGT1A9 protein expressions is significantly correlated, but not for adults aged above 18 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT1A6 and UGT1A9 correlates in the entire sample population
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additional information
in children aged below 18 years, UGT1A4 and UGT1A9 protein expressions is significantly correlated, but not for adults aged above 18 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A4 and UGT2B7 correlate more highly in male than female individuals. UGT1A4 and UGT1A6 protein correlate more significantly in female than male individuals
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additional information
in children aged below 18 years, UGT1A4 and UGT1A9 protein expressions is significantly correlated, but not for adults aged above 18 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A4 and UGT2B7 correlate more highly in male than female individuals. UGT1A4 and UGT1A6 protein correlate more significantly in female than male individuals
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additional information
in children aged below 18 years, UGT1A4 and UGT1A9 protein expressions is significantly correlated, but not for adults aged above 18 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A4 and UGT2B7 correlate more highly in male than female individuals. UGT1A4 and UGT1A6 protein correlate more significantly in female than male individuals
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additional information
in children aged below 18 years, UGT1A4 and UGT1A9 protein expressions is significantly correlated, but not for adults aged above 18 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A4 and UGT2B7 correlate more highly in male than female individuals. UGT1A4 and UGT1A6 protein correlate more significantly in female than male individuals
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additional information
in children aged below 18 years, UGT1A4 and UGT1A9 protein expressions is significantly correlated, but not for adults aged above 18 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A4 and UGT2B7 correlate more highly in male than female individuals. UGT1A4 and UGT1A6 protein correlate more significantly in female than male individuals
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additional information
in children aged below 18 years, UGT1A4 and UGT1A9 protein expressions is significantly correlated, but not for adults aged above 18 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A4 and UGT2B7 correlate more highly in male than female individuals. UGT1A4 and UGT1A6 protein correlate more significantly in female than male individuals
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additional information
in children aged below 18 years, UGT1A4 and UGT1A9 protein expressions is significantly correlated, but not for adults aged above 18 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A4 and UGT2B7 correlate more highly in male than female individuals. UGT1A4 and UGT1A6 protein correlate more significantly in female than male individuals
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additional information
in children aged below 18 years, UGT1A4 and UGT1A9 protein expressions is significantly correlated, but not for adults aged above 18 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A4 and UGT2B7 correlate more highly in male than female individuals. UGT1A4 and UGT1A6 protein correlate more significantly in female than male individuals
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additional information
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in children aged below 18 years, UGT1A4 and UGT1A9 protein expressions is significantly correlated, but not for adults aged above 18 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A4 and UGT2B7 correlate more highly in male than female individuals. UGT1A4 and UGT1A6 protein correlate more significantly in female than male individuals
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additional information
isozyme UGT3A1 expression significantly increases with age from childhood to age over 65 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT3A1 and UGT3A2 correlates in the entire sample population, but UGT3As do not correlate with other UGTs. UGT3A1/3A2 correlate more highly in male than female individuals
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additional information
isozyme UGT3A1 expression significantly increases with age from childhood to age over 65 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT3A1 and UGT3A2 correlates in the entire sample population, but UGT3As do not correlate with other UGTs. UGT3A1/3A2 correlate more highly in male than female individuals
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additional information
isozyme UGT3A1 expression significantly increases with age from childhood to age over 65 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT3A1 and UGT3A2 correlates in the entire sample population, but UGT3As do not correlate with other UGTs. UGT3A1/3A2 correlate more highly in male than female individuals
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additional information
isozyme UGT3A1 expression significantly increases with age from childhood to age over 65 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT3A1 and UGT3A2 correlates in the entire sample population, but UGT3As do not correlate with other UGTs. UGT3A1/3A2 correlate more highly in male than female individuals
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additional information
isozyme UGT3A1 expression significantly increases with age from childhood to age over 65 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT3A1 and UGT3A2 correlates in the entire sample population, but UGT3As do not correlate with other UGTs. UGT3A1/3A2 correlate more highly in male than female individuals
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additional information
isozyme UGT3A1 expression significantly increases with age from childhood to age over 65 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT3A1 and UGT3A2 correlates in the entire sample population, but UGT3As do not correlate with other UGTs. UGT3A1/3A2 correlate more highly in male than female individuals
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additional information
isozyme UGT3A1 expression significantly increases with age from childhood to age over 65 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT3A1 and UGT3A2 correlates in the entire sample population, but UGT3As do not correlate with other UGTs. UGT3A1/3A2 correlate more highly in male than female individuals
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additional information
isozyme UGT3A1 expression significantly increases with age from childhood to age over 65 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT3A1 and UGT3A2 correlates in the entire sample population, but UGT3As do not correlate with other UGTs. UGT3A1/3A2 correlate more highly in male than female individuals
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additional information
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isozyme UGT3A1 expression significantly increases with age from childhood to age over 65 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT3A1 and UGT3A2 correlates in the entire sample population, but UGT3As do not correlate with other UGTs. UGT3A1/3A2 correlate more highly in male than female individuals
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isozyme UGT3A2 expression significantly increases with age from childhood to age over 65 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT3A1 and UGT3A2 correlates in the entire sample population, but UGT3As do not correlate with other UGTs. UGT3A1/3A2 correlate more highly in male than female individuals
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additional information
isozyme UGT3A2 expression significantly increases with age from childhood to age over 65 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT3A1 and UGT3A2 correlates in the entire sample population, but UGT3As do not correlate with other UGTs. UGT3A1/3A2 correlate more highly in male than female individuals
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additional information
isozyme UGT3A2 expression significantly increases with age from childhood to age over 65 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT3A1 and UGT3A2 correlates in the entire sample population, but UGT3As do not correlate with other UGTs. UGT3A1/3A2 correlate more highly in male than female individuals
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additional information
isozyme UGT3A2 expression significantly increases with age from childhood to age over 65 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT3A1 and UGT3A2 correlates in the entire sample population, but UGT3As do not correlate with other UGTs. UGT3A1/3A2 correlate more highly in male than female individuals
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additional information
isozyme UGT3A2 expression significantly increases with age from childhood to age over 65 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT3A1 and UGT3A2 correlates in the entire sample population, but UGT3As do not correlate with other UGTs. UGT3A1/3A2 correlate more highly in male than female individuals
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additional information
isozyme UGT3A2 expression significantly increases with age from childhood to age over 65 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT3A1 and UGT3A2 correlates in the entire sample population, but UGT3As do not correlate with other UGTs. UGT3A1/3A2 correlate more highly in male than female individuals
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additional information
isozyme UGT3A2 expression significantly increases with age from childhood to age over 65 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT3A1 and UGT3A2 correlates in the entire sample population, but UGT3As do not correlate with other UGTs. UGT3A1/3A2 correlate more highly in male than female individuals
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additional information
isozyme UGT3A2 expression significantly increases with age from childhood to age over 65 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT3A1 and UGT3A2 correlates in the entire sample population, but UGT3As do not correlate with other UGTs. UGT3A1/3A2 correlate more highly in male than female individuals
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additional information
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isozyme UGT3A2 expression significantly increases with age from childhood to age over 65 years. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. Expression of UGT3A1 and UGT3A2 correlates in the entire sample population, but UGT3As do not correlate with other UGTs. UGT3A1/3A2 correlate more highly in male than female individuals
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additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A3 and UGT1A1 correlate more highly in male than female individuals
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additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A3 and UGT1A1 correlate more highly in male than female individuals
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additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A3 and UGT1A1 correlate more highly in male than female individuals
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additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A3 and UGT1A1 correlate more highly in male than female individuals
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additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A3 and UGT1A1 correlate more highly in male than female individuals
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additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A3 and UGT1A1 correlate more highly in male than female individuals
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additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A3 and UGT1A1 correlate more highly in male than female individuals
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additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A3 and UGT1A1 correlate more highly in male than female individuals
brenda
additional information
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UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A3 and UGT1A1 correlate more highly in male than female individuals
brenda
additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A4 and UGT2B7 correlate more highly in male than female individuals
brenda
additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A4 and UGT2B7 correlate more highly in male than female individuals
brenda
additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A4 and UGT2B7 correlate more highly in male than female individuals
brenda
additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A4 and UGT2B7 correlate more highly in male than female individuals
brenda
additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A4 and UGT2B7 correlate more highly in male than female individuals
brenda
additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A4 and UGT2B7 correlate more highly in male than female individuals
brenda
additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A4 and UGT2B7 correlate more highly in male than female individuals
brenda
additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A4 and UGT2B7 correlate more highly in male than female individuals
brenda
additional information
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UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. UGT1A4 and UGT2B7 correlate more highly in male than female individuals
brenda
additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. UGT1A3 and UGT1A1 correlate more highly in male than female individuals
brenda
additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. UGT1A3 and UGT1A1 correlate more highly in male than female individuals
brenda
additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. UGT1A3 and UGT1A1 correlate more highly in male than female individuals
brenda
additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. UGT1A3 and UGT1A1 correlate more highly in male than female individuals
brenda
additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. UGT1A3 and UGT1A1 correlate more highly in male than female individuals
brenda
additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. UGT1A3 and UGT1A1 correlate more highly in male than female individuals
brenda
additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. UGT1A3 and UGT1A1 correlate more highly in male than female individuals
brenda
additional information
UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. UGT1A3 and UGT1A1 correlate more highly in male than female individuals
brenda
additional information
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UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. UGT1A3 and UGT1A1 correlate more highly in male than female individuals
brenda
additional information
UGT1A6 levels are significantly higher in children than in adults. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. Expression of UGT1A6 and UGT1A9 correlates in the entire sample population. UGT1A4 and UGT1A6 protein correlate more significantly in female than male individuals
brenda
additional information
UGT1A6 levels are significantly higher in children than in adults. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. Expression of UGT1A6 and UGT1A9 correlates in the entire sample population. UGT1A4 and UGT1A6 protein correlate more significantly in female than male individuals
brenda
additional information
UGT1A6 levels are significantly higher in children than in adults. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. Expression of UGT1A6 and UGT1A9 correlates in the entire sample population. UGT1A4 and UGT1A6 protein correlate more significantly in female than male individuals
brenda
additional information
UGT1A6 levels are significantly higher in children than in adults. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. Expression of UGT1A6 and UGT1A9 correlates in the entire sample population. UGT1A4 and UGT1A6 protein correlate more significantly in female than male individuals
brenda
additional information
UGT1A6 levels are significantly higher in children than in adults. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. Expression of UGT1A6 and UGT1A9 correlates in the entire sample population. UGT1A4 and UGT1A6 protein correlate more significantly in female than male individuals
brenda
additional information
UGT1A6 levels are significantly higher in children than in adults. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. Expression of UGT1A6 and UGT1A9 correlates in the entire sample population. UGT1A4 and UGT1A6 protein correlate more significantly in female than male individuals
brenda
additional information
UGT1A6 levels are significantly higher in children than in adults. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. Expression of UGT1A6 and UGT1A9 correlates in the entire sample population. UGT1A4 and UGT1A6 protein correlate more significantly in female than male individuals
brenda
additional information
UGT1A6 levels are significantly higher in children than in adults. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. Expression of UGT1A6 and UGT1A9 correlates in the entire sample population. UGT1A4 and UGT1A6 protein correlate more significantly in female than male individuals
brenda
additional information
-
UGT1A6 levels are significantly higher in children than in adults. UGT1A3 expression is always significantly correlated with other UGT1A isoforms in all adults aged below 18 years. In individuals aged above 12 years, expression of UGT1A1/1A4, UGT1A1/1A6,UGT1A1/1A9,and UGT1A4/1A6 significantly correlates, which is not observed in children aged below 12 years. In contrast, UGT1A4/2B7 show significant correlation in children aged below 12 years,but not in individuals aged above 12 years,and this is observed in female but not male individuals. Expression of UGT1A6 and UGT1A9 correlates in the entire sample population. UGT1A4 and UGT1A6 protein correlate more significantly in female than male individuals
brenda
additional information
UGT3A1 exhibits the highest expression in liver with lower expression in aerodigestive tract tissues. Tissue expression pattern, overview
brenda
additional information
UGT3A1 exhibits the highest expression in liver with lower expression in aerodigestive tract tissues. Tissue expression pattern, overview
brenda
additional information
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UGT3A1 exhibits the highest expression in liver with lower expression in aerodigestive tract tissues. Tissue expression pattern, overview
brenda
additional information
UGT3A2 is well expressed in extrahepatic tissues. Tissue expression pattern, overview
brenda
additional information
UGT3A2 is well expressed in extrahepatic tissues. Tissue expression pattern, overview
brenda
additional information
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UGT3A2 is well expressed in extrahepatic tissues. Tissue expression pattern, overview
brenda
additional information
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wide tissue distribution
brenda