2.7.7.49: RNA-directed DNA polymerase
This is an abbreviated version!
For detailed information about RNA-directed DNA polymerase, go to the full flat file.
Word Map on EC 2.7.7.49
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2.7.7.49
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telomeres
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htert
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antiretroviral
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immortalization
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nnrti
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ribonucleoprotein
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viruses
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virological
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hiv-infected
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lymphocyte
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nonnucleoside
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zidovudine
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marrow
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lengthen
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strand
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subtype
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carcinogenesis
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tumour
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efavirenz
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retroviral
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rnase
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nevirapine
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tumorigenesis
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lamivudine
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g-quadruplexes
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anti-hiv
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drug-resistant
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cd4
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c-myc
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single-stranded
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integrase
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first-line
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alt
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tenofovir
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karyotype
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polymerases
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lifespan
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retroviruses
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ritonavir
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proviral
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polyproteins
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virion
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treatment-naive
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dntp
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indinavir
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erosion
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duplex
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p16ink4a
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hiv-positive
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papillomavirus
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medicine
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synthesis
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drug development
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analysis
- 2.7.7.49
-
telomeres
-
htert
-
antiretroviral
-
immortalization
-
nnrti
- ribonucleoprotein
- viruses
-
virological
-
hiv-infected
- lymphocyte
-
nonnucleoside
- zidovudine
- marrow
-
lengthen
- strand
- subtype
- carcinogenesis
- tumour
- efavirenz
-
retroviral
- rnase
- nevirapine
- tumorigenesis
- lamivudine
-
g-quadruplexes
-
anti-hiv
-
drug-resistant
- cd4
- c-myc
-
single-stranded
-
integrase
-
first-line
-
alt
- tenofovir
-
karyotype
- polymerases
-
lifespan
- retroviruses
- ritonavir
-
proviral
- polyproteins
- virion
-
treatment-naive
- dntp
- indinavir
-
erosion
- duplex
- p16ink4a
-
hiv-positive
- papillomavirus
- medicine
- synthesis
- drug development
- analysis
Reaction
Synonyms
Bst DNA polymerase, CS5 pol, DNA nucleotidyltransferase (RNA-directed), DNA polymerase, DNA polymerase I, FeLV RT, FIV RT, FV Pol, FV reverse transcriptase, Gag-Pol, HBV-pol, HIV reverse transcriptase, HIV-1 M RT, HIV-1 O RT, HIV-1 R, HIV-1 reverse transcriptase, HIV-1 RT, HIV-reverse transcriptase, HIV-RT, human hepatitis B virus polymerase, human immunodeficiency virus type 1 reverse transcriptase, iScript enzyme, K4 polymerase, K4PolI, M-MuLV reverse transcriptase, MMLV RT, Moloney Murine leukemia virus reverse transcriptase, Moloney murine leukemia virus RT, MoMLV RT, More, MuLV RT, MX162-RT, MX65-RT, nucleoside reverse transcriptase, nucleotidyltransferase, deoxyribonucleate, RNA-dependent, p66 RT, P72, PFV RT, Pol, polymerase/reverse transcriptase, prototype foamy virus reverse transcriptase, R2-RT, reverse transcriptase, reverse transcriptase/RNA dependent DNA polymerase, reverse-transcriptase, revertase, RNA dependent DNA polymerase, RNA revertase, RNA-dependent DNA polymerase, RNA-instructed DNA polymerase, RT, SFV RT, simian foamy virus reverse transcriptase, SS RT, SuperScript I reverse transcriptase, Superscript II, SUPERSCRIPT II reverse transcriptase, T. Z05 pol, telomerase, telomerase catalytic subunit, telomerase reverse transcriptase, TERT, Tgo-Pol, xenotropic murine leukemia virus-related virus reverse transcriptase, XMRV RT, XNA reverse transcriptase
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2.7.7.49 RNA-directed DNA polymeraseAdvanced search results
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results (Organism
Organism on EC 2.7.7.49 - RNA-directed DNA polymerase
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ORGANISM 
COMMENTARY 
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
Hamster leukemia virus
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643414, 643415, 643417, 643418, 643419, 643422, 643426, 643435, 643437, 643439, 643441, 643442, 643443, 643445, 695237, 703356
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wild-type and 3'-azido-3'-deoxythymidine resistant strain D67N/K70R/T215Y/K219Q
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674913, 691140, 691152, 691632, 691882, 691981, 692248, 692539, 692555, 692567, 692580, 692582, 692597, 693312, 693914, 694207, 694309, 694504, 695141, 695224
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DNA polymerase Pol gamma also catalyzes reverse transcription with a slightly higher efficiency than HIV-1 reverse transcriptase
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human LINE-1 ORF2, which encodes reverse transcriptase, is inserted into a baculovirus shuttle vector and expressed in SF21 cells
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643452, 660996, 661160, 661197, 661221, 661719, 662208, 662228, 662263, 662425, 662652, 663342, 671562, 671783
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694787, 695260, 695261, 714972, 716827, 721138, 721815, 721816, 721995, 722241, 722692, 723042, 723089, 723239, 723294, 723783, 729231, 737458, 737464, 737639, 737824, 738666, 738778, 739043, 739126, 760694, 761475, 761495, 761679
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Escherichia coli BL21 transfected with pET 21a(+)/HIV-1 PR-RT
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group O and M virus, Group O infection is restricted to Cameroon and neighboring countries in West Central Africa, while Group M infection is spread all over the world
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multi-drug resistant (MR) HIV-1 reverse transcriptase, subcloned from a patient derived subtype CRF02 AG, harboring 45 amino acid exchanges, amongst them four thymidine analog mutations (TAMs) relevant for high-level AZT (azidothymidine) resistance by AZTMP excision (M41L, D67N, T215Y, K219E) as well as four substitutions of the AZTTP discrimination pathway (A62V, V75I, F116Y and Q151M). In addition, K65R, known to antagonize AZTMP excision in HIV-1 subtype B is present
UniProt
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681096, 691513, 692219, 693073, 693484, 693960, 694030, 695179, 703356, 721311, 721508, 723292, 723690, 737601
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mutant version of reverse trancriptase from retrotransposon Ty1, in which one of the three active site aspartates is changed to asparagine, D211N
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